Gene detail

NG853_RS02620

Histidine kinase, Classic

Enterococcus faecium · GCF_023956545

ClassHKTypeClassicLength501 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_023956545#NG853_RS02620Stable P2CS identifier used across views.
GenomeGCF_023956545Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1468395Run 6 · 118 sequences · id 100% · cov 80%
External referencesWP_002336942.1 · A0AAW8RKX6 · MIST4 NG853_RS02620RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length501 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage249 / 501 aa (49.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa501 aa
HAMP: 198-268 aa (71 aa)1HisKA: 273-339 aa (67 aa)2HATPase_c: 387-497 aa (111 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
198-268 aa · 71 aa · 14.2% of protein
Raw tokenHAMP:198:0.000000000000577:268:71:69
2 HisKA#2
273-339 aa · 67 aa · 13.4% of protein
Raw tokenHisKA:273:0.00000000000000337:339:67:64
3 HATPase_c#3
387-497 aa · 111 aa · 22.2% of protein
Raw tokenHATPase_c:387:8.21e-28:497:111:109
  • Raw architecture: HAMP:198:0.000000000000577:268:71:69#HisKA:273:0.00000000000000337:339:67:64#HATPase_c:387:8.21e-28:497:111:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_023956545::NZ_JAMXGQ010000007.1::G00015
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span614-2802Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNG853_02620RefSeq proteinWP_002336942.1
Context group IDGCF_023956545::NZ_JAMXGQ010000007.1::G00015
Context members
NG853_RS02620NG853_RS02625
Partner locus tags
NG853_RS02620NG853_RS02625
Partner old locus tags
NG853_02620NG853_02625
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002336942.1Primary protein accession used for annex mappings.
UniProt accessionA0AAW8RKX6Primary UniProt accession resolved in the annex database.
UniProt IDA0AAW8RKX6_ENTFCDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNG853_RS02620Primary locus identifier stored in the genes table.
Old locus tagNG853_02620Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAMXGQ010000007.1Sequence record reported by the local genomic context database.
Genomic interval614-2 119 nt1 506 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span614-2 802 ntGCF_023956545::NZ_JAMXGQ010000007.1::G00015

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_023956545::NZ_JAMXGQ010000007.1::G00015

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAMXGQ010000007.1All displayed genes belong to this local TCS context.
Neighborhood span614-2 802 nt2 189 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
614 nt2 802 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NG853_RS02620GCF_023956545#NG853_RS02620
HKClassicCurrent focus

614-2 119 nt · Reverse (-)

Old locus NG853_02620RefSeq WP_002336942.1
NG853_RS02625GCF_023956545#NG853_RS02625
RROmpR

2 116-2 802 nt · Reverse (-)

Old locus NG853_02625RefSeq WP_002290973.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1468395Run 6 · HK · 118 sequences
Representative sequenceGCF_000321925#OIK_RS11180Use this link to inspect the representative gene detail.
PFAM architectureArlS_N + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1468395

Simplified PFAM architecture for HKOC_1468395

PFAM domain coverage: 377 / 501 aa (75.2%)

1 aa501 aa
ArlS_N: 46-193 aaArlS_NHAMP: 215-268 aaHAMPHisKA: 274-339 aaHisKAHATPase_c: 388-496 aaHATPase_c
ArlS_NHAMPHisKAHATPase_c
  • Simplified architecture: ArlS_N + HAMP + HisKA + HATPase_c
  • Raw architecture: ArlS_N[46-193] | HAMP[215-268] | HisKA[274-339] | HATPase_c[388-496]
  • Domain count: 4
  • Matched identifier: HKOC_1468395
  • Positioned domains: ArlS_N 46-193 ; HAMP 215-268 ; HisKA 274-339 ; HATPase_c 388-496
Cluster members and taxonomy
Visualization

Representative gene: GCF_000321925#OIK_RS11180

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 352 · GCF_023956545
AssemblyASM2395654v1 · Contighaploid
Genome composition2 546 321 bp · 38,0% GCEnterococcus faecium
Signal transduction countsGenes 29 · HK 15 · RR 14CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key