Gene detail

NG853_RS00335

Histidine kinase, Classic

Enterococcus faecium · GCF_023956545

ClassHKTypeClassicLength298 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_023956545#NG853_RS00335Stable P2CS identifier used across views.
GenomeGCF_023956545Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_2888679Run 6 · 332 sequences · id 100% · cov 80%
External referencesWP_002326086.1 · A0AB37VU34 · MIST4 NG853_RS00335RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length298 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage165 / 298 aa (55.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa298 aa
HisKA: 87-144 aa (58 aa)1HATPase_c: 191-297 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
87-144 aa · 58 aa · 19.5% of protein
Raw tokenHisKA:87:0.000000000000118:144:58:64
2 HATPase_c#2
191-297 aa · 107 aa · 35.9% of protein
Raw tokenHATPase_c:191:3.77e-16:297:111:109
  • Raw architecture: HisKA:87:0.000000000000118:144:58:64#HATPase_c:191:3.77e-16:297:111:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_023956545::NZ_JAMXGQ010000001.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span71195-72764Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNG853_00335RefSeq proteinWP_002326086.1
Context group IDGCF_023956545::NZ_JAMXGQ010000001.1::G00001
Context members
NG853_RS00335NG853_RS00340
Partner locus tags
NG853_RS00335NG853_RS00340
Partner old locus tags
NG853_00335NG853_00340
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002326086.1Primary protein accession used for annex mappings.
UniProt accessionA0AB37VU34Primary UniProt accession resolved in the annex database.
UniProt IDA0AB37VU34_ENTFCDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNG853_RS00335Primary locus identifier stored in the genes table.
Old locus tagNG853_00335Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAMXGQ010000001.1Sequence record reported by the local genomic context database.
Genomic interval71 195-72 091 nt897 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span71 195-72 764 ntGCF_023956545::NZ_JAMXGQ010000001.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_023956545::NZ_JAMXGQ010000001.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAMXGQ010000001.1All displayed genes belong to this local TCS context.
Neighborhood span71 195-72 764 nt1 570 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
71 195 nt72 764 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NG853_RS00335GCF_023956545#NG853_RS00335
HKClassicCurrent focus

71 195-72 091 nt · Reverse (-)

Old locus NG853_00335RefSeq WP_002326086.1
NG853_RS00340GCF_023956545#NG853_RS00340
RROmpR

72 084-72 764 nt · Reverse (-)

Old locus NG853_00340RefSeq WP_002324452.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2888679Run 6 · HK · 332 sequences
Representative sequenceGCF_000321465#OG9_RS16560Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2888679

Simplified PFAM architecture for HKOC_2888679

PFAM domain coverage: 157 / 298 aa (52.7%)

1 aa298 aa
HisKA: 87-144 aaHisKAHATPase_c: 192-290 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[87-144] | HATPase_c[192-290]
  • Domain count: 2
  • Matched identifier: HKOC_2888679
  • Positioned domains: HisKA 87-144 ; HATPase_c 192-290
Cluster members and taxonomy
Visualization

Representative gene: GCF_000321465#OG9_RS16560

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 352 · GCF_023956545
AssemblyASM2395654v1 · Contighaploid
Genome composition2 546 321 bp · 38,0% GCEnterococcus faecium
Signal transduction countsGenes 29 · HK 15 · RR 14CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key