Gene detail

M3689_RS00570

Histidine kinase, Classic

Alkalihalophilus marmarensis · GCF_023712545

ClassHKTypeClassicLength593 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_023712545#M3689_RS00570Stable P2CS identifier used across views.
GenomeGCF_023712545Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Alkalihalophilus
Selected clusterHKOC_1093117Run 6 · 2 sequences · id 100% · cov 80%
External referencesWP_022628831.1 · U6SLB3 · MIST4 M3689_RS00570RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

sCache_likeHAMPPASHisKAHATPase_c
Protein length593 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage470 / 593 aa (79.3%)Merged over positioned domains only.
Domain description1 sCache_like,1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa593 aa
sCache_like: 35-151 aa (117 aa)1HAMP: 167-236 aa (70 aa)2PAS: 246-353 aa (108 aa)3HisKA: 363-428 aa (66 aa)4HATPase_c: 474-582 aa (109 aa)5
Domain-by-domain annotation5 items
1 sCache_like#1
35-151 aa · 117 aa · 19.7% of protein
Raw tokensCache_like:35:5.05e-25:151:117:114
2 HAMP#2
167-236 aa · 70 aa · 11.8% of protein
Raw tokenHAMP:167:0.0000000000322:236:70:69
3 PAS#3
246-353 aa · 108 aa · 18.2% of protein
Raw tokenPAS:246:0.0000000000576:353:113:113
4 HisKA#4
363-428 aa · 66 aa · 11.1% of protein
Raw tokenHisKA:363:2.65e-17:428:66:64
5 HATPase_c#5
474-582 aa · 109 aa · 18.4% of protein
Raw tokenHATPase_c:474:2.54e-34:582:109:109
  • Raw architecture: sCache_like:35:5.05e-25:151:117:114#HAMP:167:0.0000000000322:236:70:69#PAS:246:0.0000000000576:353:113:113#HisKA:363:2.65e-17:428:66:64#HATPase_c:474:2.54e-34:582:109:109
  • Domain description: 1 sCache_like,1 HAMP,1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_023712545::NZ_JAMAYA010000001.1::G00015
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span119367-121866Genomic interval covered by the local TCS group.
Identifiers
Old locus tagM3689_00570RefSeq proteinWP_022628831.1
Context group IDGCF_023712545::NZ_JAMAYA010000001.1::G00015
Context members
M3689_RS00565M3689_RS00570
Partner locus tags
M3689_RS00565M3689_RS00570
Partner old locus tags
M3689_00565M3689_00570
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_022628831.1Primary protein accession used for annex mappings.
UniProt accessionU6SLB3Primary UniProt accession resolved in the annex database.
UniProt IDU6SLB3_9BACIDisplay identifier provided by UniProt.
GO / PubMed6 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagM3689_RS00570Primary locus identifier stored in the genes table.
Old locus tagM3689_00570Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAMAYA010000001.1Sequence record reported by the local genomic context database.
Genomic interval120 085-121 866 nt1 782 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span119 367-121 866 ntGCF_023712545::NZ_JAMAYA010000001.1::G00015

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_023712545::NZ_JAMAYA010000001.1::G00015

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAMAYA010000001.1All displayed genes belong to this local TCS context.
Neighborhood span119 367-121 866 nt2 500 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
119 367 nt121 866 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

M3689_RS00565GCF_023712545#M3689_RS00565
RROmpR

119 367-120 092 nt · Forward (+)

Old locus M3689_00565RefSeq WP_012960013.1
M3689_RS00570GCF_023712545#M3689_RS00570
HKClassicCurrent focus

120 085-121 866 nt · Forward (+)

Old locus M3689_00570RefSeq WP_022628831.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1093117Run 6 · HK · 2 sequences
Representative sequenceGCF_000474275#A33I_RS13085Use this link to inspect the representative gene detail.
PFAM architecturesCache_like + HAMP + PAS + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1093117

Simplified PFAM architecture for HKOC_1093117

PFAM domain coverage: 454 / 593 aa (76.6%)

1 aa593 aa
sCache_like: 33-151 aasCache_likeHAMP: 185-235 aaHAMPPAS: 246-353 aaPASHisKA: 363-428 aaHisKAHATPase_c: 474-583 aaHATPase_c
sCache_likeHAMPPASHisKAHATPase_c
  • Simplified architecture: sCache_like + HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: sCache_like[33-151] | HAMP[185-235] | PAS[246-353] | HisKA[363-428] | HATPase_c[474-583]
  • Domain count: 5
  • Matched identifier: HKOC_1093117
  • Positioned domains: sCache_like 33-151 ; HAMP 185-235 ; PAS 246-353 ; HisKA 363-428 ; HATPase_c 474-583
Cluster members and taxonomy
Visualization

Representative gene: GCF_000474275#A33I_RS13085

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 521 377 · GCF_023712545
AssemblyASM2371254v1 · Contighaploid
Genome composition4 103 950 bp · 40,0% GCAlkalihalophilus marmarensis
Signal transduction countsGenes 71 · HK 38 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusAlkalihalophilus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Alkalihalophilus

Related genes

Preview from the same derived genome key