Gene detail

MR568_RS04480

Histidine kinase, Classic

Eisenbergiella massiliensis · GCF_022781285

ClassHKTypeClassicLength575 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_022781285#MR568_RS04480Stable P2CS identifier used across views.
GenomeGCF_022781285Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Eisenbergiella
Selected clusterHKOC_1190520Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_276913761.1 · MIST4 MR568_RS04480RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length575 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage464 / 575 aa (80.7%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa575 aa
dCache_1: 48-257 aa (210 aa)1HAMP: 278-344 aa (67 aa)2His_kinase: 366-443 aa (78 aa)3HATPase_c: 463-571 aa (109 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
48-257 aa · 210 aa · 36.5% of protein
Raw tokendCache_1:48:0.0000154:257:229:195
2 HAMP#2
278-344 aa · 67 aa · 11.7% of protein
Raw tokenHAMP:278:0.0000116:344:67:69
3 His_kinase#3
366-443 aa · 78 aa · 13.6% of protein
Raw tokenHis_kinase:366:1.17e-26:443:79:80
4 HATPase_c#4
463-571 aa · 109 aa · 19.0% of protein
Raw tokenHATPase_c:463:0.0000000000000101:571:109:109
  • Raw architecture: dCache_1:48:0.0000154:257:229:195#HAMP:278:0.0000116:344:67:69#His_kinase:366:1.17e-26:443:79:80#HATPase_c:463:0.0000000000000101:571:109:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_022781285::NZ_JALETP010000058.1::G00072
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span24249-26725Genomic interval covered by the local TCS group.
Identifiers
Old locus tagMR568_04515RefSeq proteinWP_276913761.1
Context group IDGCF_022781285::NZ_JALETP010000058.1::G00072
Context members
MR568_RS04475MR568_RS04480
Partner locus tags
MR568_RS04475MR568_RS04480
Partner old locus tags
MR568_04510MR568_04515
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_276913761.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagMR568_RS04480Primary locus identifier stored in the genes table.
Old locus tagMR568_04515Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JALETP010000058.1Sequence record reported by the local genomic context database.
Genomic interval24 998-26 725 nt1 728 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span24 249-26 725 ntGCF_022781285::NZ_JALETP010000058.1::G00072

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_022781285::NZ_JALETP010000058.1::G00072

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JALETP010000058.1All displayed genes belong to this local TCS context.
Neighborhood span24 249-26 725 nt2 477 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
24 249 nt26 725 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

MR568_RS04475GCF_022781285#MR568_RS04475
RRunclassified

24 249-24 995 nt · Reverse (-)

Old locus MR568_04510RefSeq WP_276913759.1
MR568_RS04480GCF_022781285#MR568_RS04480
HKClassicCurrent focus

24 998-26 725 nt · Reverse (-)

Old locus MR568_04515RefSeq WP_276913761.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1190520Run 6 · HK · 2 sequences
Representative sequenceGCF_022781285#MR568_RS04480The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1190520

Simplified PFAM architecture for HKOC_1190520

PFAM domain coverage: 187 / 575 aa (32.5%)

1 aa575 aa
His_kinase: 367-442 aaHis_kinaseHATPase_c: 462-572 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[367-442] | HATPase_c[462-572]
  • Domain count: 2
  • Matched identifier: HKOC_1190520
  • Positioned domains: His_kinase 367-442 ; HATPase_c 462-572
Cluster members and taxonomy
Visualization

Representative gene: GCF_022781285#MR568_RS04480

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 720 294 · GCF_022781285
AssemblyASM2278128v1 · Contighaploid
Genome composition5 340 195 bp · 48,5% GCEisenbergiella massiliensis
Signal transduction countsGenes 161 · HK 74 · RR 79CheA 0 · PP 8
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusEisenbergiella
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Eisenbergiella

Related genes

Preview from the same derived genome key