Gene detail

I2D69_RS06280

Histidine kinase, Classic

Ruminococcus sp. D54t1_190329_F1 · GCF_015551645

ClassHKTypeClassicLength577 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015551645#I2D69_RS06280Stable P2CS identifier used across views.
GenomeGCF_015551645Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Ruminococcus
Selected clusterHKOC_1179248Run 6 · 6 sequences · id 100% · cov 80%
External referencesWP_173715717.1 · MIST4 I2D69_RS06280RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length577 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage242 / 577 aa (41.9%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa577 aa
HAMP: 304-372 aa (69 aa)1His_kinase: 387-466 aa (80 aa)2HATPase_c: 485-577 aa (93 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
304-372 aa · 69 aa · 12.0% of protein
Raw tokenHAMP:304:0.000000000351:372:69:69
2 His_kinase#2
387-466 aa · 80 aa · 13.9% of protein
Raw tokenHis_kinase:387:9.4e-28:466:80:80
3 HATPase_c#3
485-577 aa · 93 aa · 16.1% of protein
Raw tokenHATPase_c:485:0.00000000967:577:108:109
  • Raw architecture: HAMP:304:0.000000000351:372:69:69#His_kinase:387:9.4e-28:466:80:80#HATPase_c:485:0.00000000967:577:108:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_015551645::NZ_JADNDC010000010.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span55994-58832Genomic interval covered by the local TCS group.
Context group IDGCF_015551645::NZ_JADNDC010000010.1::G00002
Context members
I2D69_RS06275I2D69_RS06280
Partner locus tags
I2D69_RS06275I2D69_RS06280
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_173715717.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagI2D69_RS06280Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JADNDC010000010.1Sequence record reported by the local genomic context database.
Genomic interval57 099-58 832 nt1 734 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span55 994-58 832 ntGCF_015551645::NZ_JADNDC010000010.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015551645::NZ_JADNDC010000010.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JADNDC010000010.1All displayed genes belong to this local TCS context.
Neighborhood span55 994-58 832 nt2 839 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
55 994 nt58 832 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

I2D69_RS06275GCF_015551645#I2D69_RS06275
RRunclassified

55 994-57 064 nt · Reverse (-)

RefSeq WP_173769400.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1179248Run 6 · HK · 6 sequences
Representative sequenceGCF_013300155#G4470_RS02145Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1179248

Simplified PFAM architecture for HKOC_1179248

PFAM domain coverage: 175 / 577 aa (30.3%)

1 aa577 aa
His_kinase: 387-466 aaHis_kinaseHATPase_c: 482-576 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[387-466] | HATPase_c[482-576]
  • Domain count: 2
  • Matched identifier: HKOC_1179248
  • Positioned domains: His_kinase 387-466 ; HATPase_c 482-576
Cluster members and taxonomy
Visualization

Representative gene: GCF_013300155#G4470_RS02145

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 787 114 · GCF_015551645
AssemblyASM1555164v1 · Scaffoldhaploid
Genome composition4 332 946 bp · 43,0% GCRuminococcus sp. D54t1_190329_F1
Signal transduction countsGenes 138 · HK 68 · RR 69CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusRuminococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Ruminococcus

Related genes

Preview from the same derived genome key