Gene detail

G4476_RS02850

Histidine kinase, Classic

Blautia wexlerae · GCF_013301775

ClassHKTypeClassicLength599 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_013301775#G4476_RS02850Stable P2CS identifier used across views.
GenomeGCF_013301775Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1058948Run 6 · 10 sequences · id 100% · cov 80%
External referencesWP_173684403.1 · MIST4 G4476_RS02850RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length599 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage487 / 599 aa (81.3%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa599 aa
dCache_1: 38-268 aa (231 aa)1HAMP: 285-354 aa (70 aa)2His_kinase: 369-448 aa (80 aa)3HATPase_c: 464-569 aa (106 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
38-268 aa · 231 aa · 38.6% of protein
Raw tokendCache_1:38:0.00000000000000582:268:235:195
2 HAMP#2
285-354 aa · 70 aa · 11.7% of protein
Raw tokenHAMP:285:0.0000000581:354:70:69
3 His_kinase#3
369-448 aa · 80 aa · 13.4% of protein
Raw tokenHis_kinase:369:4.69e-34:448:80:80
4 HATPase_c#4
464-569 aa · 106 aa · 17.7% of protein
Raw tokenHATPase_c:464:0.000000000000178:569:109:109
  • Raw architecture: dCache_1:38:0.00000000000000582:268:235:195#HAMP:285:0.0000000581:354:70:69#His_kinase:369:4.69e-34:448:80:80#HATPase_c:464:0.000000000000178:569:109:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_013301775::NZ_JAAIOX010000006.1::G00053
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4990-8460Genomic interval covered by the local TCS group.
Identifiers
Old locus tagG4476_02865RefSeq proteinWP_173684403.1
Context group IDGCF_013301775::NZ_JAAIOX010000006.1::G00053
Context members
G4476_RS02845G4476_RS02850
Partner locus tags
G4476_RS02845G4476_RS02850
Partner old locus tags
G4476_02860G4476_02865
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_173684403.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagG4476_RS02850Primary locus identifier stored in the genes table.
Old locus tagG4476_02865Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAIOX010000006.1Sequence record reported by the local genomic context database.
Genomic interval6 661-8 460 nt1 800 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 990-8 460 ntGCF_013301775::NZ_JAAIOX010000006.1::G00053

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_013301775::NZ_JAAIOX010000006.1::G00053

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAIOX010000006.1All displayed genes belong to this local TCS context.
Neighborhood span4 990-8 460 nt3 471 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 990 nt8 460 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

G4476_RS02845GCF_013301775#G4476_RS02845
RRunclassified

4 990-6 588 nt · Forward (+)

Old locus G4476_02860RefSeq WP_173684386.1
G4476_RS02850GCF_013301775#G4476_RS02850
HKClassicCurrent focus

6 661-8 460 nt · Forward (+)

Old locus G4476_02865RefSeq WP_173684403.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1058948Run 6 · HK · 10 sequences
Representative sequenceGCF_013299815#G4455_RS09420Use this link to inspect the representative gene detail.
PFAM architecturedCache_1 + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1058948

Simplified PFAM architecture for HKOC_1058948

PFAM domain coverage: 416 / 599 aa (69.4%)

1 aa599 aa
dCache_1: 39-268 aadCache_1His_kinase: 369-448 aaHis_kinaseHATPase_c: 465-570 aaHATPase_c
dCache_1His_kinaseHATPase_c
  • Simplified architecture: dCache_1 + His_kinase + HATPase_c
  • Raw architecture: dCache_1[39-268] | His_kinase[369-448] | HATPase_c[465-570]
  • Domain count: 3
  • Matched identifier: HKOC_1058948
  • Positioned domains: dCache_1 39-268 ; His_kinase 369-448 ; HATPase_c 465-570
Cluster members and taxonomy
Visualization

Representative gene: GCF_013299815#G4455_RS09420

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 418 240 · GCF_013301775
AssemblyASM1330177v1 · Contighaploid
Genome composition4 087 349 bp · 41,0% GCBlautia wexlerae
Signal transduction countsGenes 123 · HK 61 · RR 61CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key