Gene detail

G4476_RS01170

Histidine kinase, Classic

Blautia wexlerae · GCF_013301775

ClassHKTypeClassicLength614 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_013301775#G4476_RS01170Stable P2CS identifier used across views.
GenomeGCF_013301775Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_0991290Run 6 · 94 sequences · id 100% · cov 80%
External referencesWP_025578107.1 · A0A173YIF6 · MIST4 G4476_RS01170RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length614 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage258 / 614 aa (42.0%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa614 aa
HAMP: 310-379 aa (70 aa)1His_kinase: 401-480 aa (80 aa)2HATPase_c: 500-607 aa (108 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
310-379 aa · 70 aa · 11.4% of protein
Raw tokenHAMP:310:0.0000000000399:379:70:69
2 His_kinase#2
401-480 aa · 80 aa · 13.0% of protein
Raw tokenHis_kinase:401:2.3e-23:480:80:80
3 HATPase_c#3
500-607 aa · 108 aa · 17.6% of protein
Raw tokenHATPase_c:500:2.64e-16:607:108:109
  • Raw architecture: HAMP:310:0.0000000000399:379:70:69#His_kinase:401:2.3e-23:480:80:80#HATPase_c:500:2.64e-16:607:108:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_013301775::NZ_JAAIOX010000002.1::G00026
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span116169-118804Genomic interval covered by the local TCS group.
Identifiers
Old locus tagG4476_01180RefSeq proteinWP_025578107.1
Context group IDGCF_013301775::NZ_JAAIOX010000002.1::G00026
Context members
G4476_RS01170G4476_RS01175
Partner locus tags
G4476_RS01170G4476_RS01175
Partner old locus tags
G4476_01180G4476_01185
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_025578107.1Primary protein accession used for annex mappings.
UniProt accessionA0A173YIF6Primary UniProt accession resolved in the annex database.
UniProt IDA0A173YIF6_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagG4476_RS01170Primary locus identifier stored in the genes table.
Old locus tagG4476_01180Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAIOX010000002.1Sequence record reported by the local genomic context database.
Genomic interval116 169-118 013 nt1 845 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span116 169-118 804 ntGCF_013301775::NZ_JAAIOX010000002.1::G00026

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_013301775::NZ_JAAIOX010000002.1::G00026

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAIOX010000002.1All displayed genes belong to this local TCS context.
Neighborhood span116 169-118 804 nt2 636 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
116 169 nt118 804 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

G4476_RS01170GCF_013301775#G4476_RS01170
HKClassicCurrent focus

116 169-118 013 nt · Forward (+)

Old locus G4476_01180RefSeq WP_025578107.1
G4476_RS01175GCF_013301775#G4476_RS01175
RRunclassified

118 055-118 804 nt · Forward (+)

Old locus G4476_01185RefSeq WP_055149581.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0991290Run 6 · HK · 94 sequences
Representative sequenceGCF_000484655#K316_RS0106325Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0991290

Simplified PFAM architecture for HKOC_0991290

PFAM domain coverage: 237 / 614 aa (38.6%)

1 aa614 aa
HAMP: 327-378 aaHAMPHis_kinase: 401-478 aaHis_kinaseHATPase_c: 500-606 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[327-378] | His_kinase[401-478] | HATPase_c[500-606]
  • Domain count: 3
  • Matched identifier: HKOC_0991290
  • Positioned domains: HAMP 327-378 ; His_kinase 401-478 ; HATPase_c 500-606
Cluster members and taxonomy
Visualization

Representative gene: GCF_000484655#K316_RS0106325

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 418 240 · GCF_013301775
AssemblyASM1330177v1 · Contighaploid
Genome composition4 087 349 bp · 41,0% GCBlautia wexlerae
Signal transduction countsGenes 123 · HK 61 · RR 61CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key