Gene detail

FNA57_RS00720

Histidine kinase, Classic

Francisella tularensis · GCF_009814095

Open genome Open selected cluster RefSeq UniProt

ClassHKTypeClassicLength475 aaTM2ValidatedNoCompleteYesContextorphan

Gene IDGCF_009814095#FNA57_RS00720Stable P2CS identifier used across views.

GenomeGCF_009814095Unknown

Selected clusterHKOC_1664347Run 6 · 726 sequences · id 100% · cov 80%

External referencesWP_003017277.1 · A0AAI8FTV0 · MIST4 FNA57_RS00720RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c2 TM helices

Protein length475 aaLength used to scale native and Biotite-like views.

Annotated domains22 with usable coordinates.

Domain coverage167 / 475 aa (35.2%)Merged over positioned domains only.

Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.

Signal peptideNot predictedFrom HK/TM SQLite database.

Transmembrane helices16-37 aa · 22 aa · 174-196 aa · 23 aa2 helices reported by HK/TM SQLite database.

Complete domain annotations

Domain view

Native Biotite-like

Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.

1 aa475 aa

Domain-by-domain annotation2 items

1 HisKA#1

252-312 aa · 61 aa · 12.8% of protein

Raw tokenHisKA:252:0.0000000000000889:312:61:64

2 HATPase_c#2

365-470 aa · 106 aa · 22.3% of protein

Raw tokenHATPase_c:365:3.68e-29:470:106:109

Raw architecture: HisKA:252:0.0000000000000889:312:61:64#HATPase_c:365:3.68e-29:470:106:109
Domain description: 1 HisKA,1 HATPase_c
TM description: N/A
TMPRED source: HK/TM SQLite database
TMPRED segments: TM helix 16-37; TM helix 174-196
Complete: Yes

Protein sequence

On-demand local amino-acid sequence in FASTA format

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_009814095::NZ_VJBX01000002.1::G00001

Group size11 locus tag listed below.

HK / RR1 / 0Counts resolved for the local TCS neighborhood.

Context span51827-53254Genomic interval covered by the local TCS group.

Identifiers

Old locus tagFNA57_00735RefSeq proteinWP_003017277.1

Context group IDGCF_009814095::NZ_VJBX01000002.1::G00001

Context members

FNA57_RS00720

Partner locus tags

FNA57_RS00720

Partner old locus tags

FNA57_00735

Partner protein IDs

WP_003017277.1

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003017277.1Primary protein accession used for annex mappings.

UniProt accessionA0AAI8FTV0Primary UniProt accession resolved in the annex database.

UniProt IDA0AAI8FTV0_FRATHDisplay identifier provided by UniProt.

GO / PubMed3 / 1Unique GO terms and literature references available below.

Reference hubs

Open RefSeq Open UniProt accession

GO terms

GO:0005886 GO:0005524 GO:0000155

PubMed

25931589

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagFNA57_RS00720Primary locus identifier stored in the genes table.

Old locus tagFNA57_00735Legacy locus tag recovered from the local context mapping.

Contig / repliconNZ_VJBX01000002.1Sequence record reported by the local genomic context database.

Genomic interval51 827-53 254 nt1 428 nt · Reverse (-)

StrandReverse (-)Strand sign follows the local context database convention.

Local TCS group span51 827-53 254 ntGCF_009814095::NZ_VJBX01000002.1::G00001

Quick actions

Open genome Search genes in genome

Genome neighborhood

Gene-centered window parsed directly from the configured gzipped GFF annotation

GCF_009814095 · NZ_VJBX01000002.1

Graphic view

Compact Biotite-like

Zoom

Full window Focus gene

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Centered locusFNA57_RS0072010 genes displayed around the current focus.

Configured flank5 upstream / downstreamWindow size loaded from config.ini.

Annotation sourceGCF_009814095.gff.gzResolved as <gff_root_dir>/<genome_id>/<genome_id>.gff.gz when available.

View modeGene-centered orderThis track keeps the current gene in the middle of the context window when possible.

Gene-centered contextFive upstream and five downstream genes can be shown when the configured flank count is set to 5.

Current geneHKRROther P2CSOutside P2CS

FNA57_RS00700FNA57_RS00700

FNA57_RS00705FNA57_RS00705

FNA57_RS00710FNA57_RS00710

FNA57_RS10690FNA57_RS10690

FNA57_RS00715FNA57_RS00715

6FNA57_RS00720FNA57_RS00720

FNA57_RS00725FNA57_RS00725

FNA57_RS00730FNA57_RS00730

FNA57_RS10695FNA57_RS10695

FNA57_RS00740FNA57_RS00740

Neighborhood gene cards

10 genes in the current genome window.

FNA57_RS00700FNA57_RS00700

Outside P2CS

47 926-48 360 nt · 435 nt · Reverse (-)

DUF3429 domain-containing protein

Protein WP_010031434.1

FNA57_RS00705FNA57_RS00705

Outside P2CS

48 371-49 333 nt · 963 nt · Reverse (-)

cytochrome d ubiquinol oxidase subunit II

Protein WP_003017283.1

FNA57_RS00710FNA57_RS00710

Outside P2CS

49 337-50 431 nt · 1 095 nt · Reverse (-)

cytochrome ubiquinol oxidase subunit I

Protein WP_012119046.1

FNA57_RS10690FNA57_RS10690

Outside P2CS

50 385-50 801 nt · 417 nt · Forward (+)

hypothetical protein

Protein WP_010031438.1

FNA57_RS00715FNA57_RS00715

Outside P2CS

50 949-51 830 nt · 882 nt · Forward (+)

TIGR01777 family oxidoreductase

Protein WP_003017280.1

FNA57_RS00720FNA57_RS00720

HKClassicCurrent focus

51 827-53 254 nt · 1 428 nt · Reverse (-)

sensor histidine kinase

Protein WP_003017277.1Histidine kinase, Classic

FNA57_RS00725FNA57_RS00725

Outside P2CS

53 370-54 323 nt · 954 nt · Forward (+)

hypothetical protein

FNA57_RS00730FNA57_RS00730

Outside P2CS

54 327-55 607 nt · 1 281 nt · Forward (+)

ATP-grasp domain-containing protein

FNA57_RS10695FNA57_RS10695

Outside P2CS

55 995-56 279 nt · 285 nt · Forward (+)

hypothetical protein

Protein WP_011457531.1

FNA57_RS00740FNA57_RS00740

Outside P2CS

56 257-56 377 nt · 121 nt · Reverse (-)

IS630 family transposase

3D Structure

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Available memberships1 cluster

HKOC_1664347HK

Run 6726 sequencesid 100%cov 80%

PFAM HisKA + HATPase_c

Representative GCF_000009245#FTL_RS09010

Selected clusterHKOC_1664347Run 6 · HK · 726 sequences

Representative sequenceGCF_000009245#FTL_RS09010Use this link to inspect the representative gene detail.

PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

Open in cluster search Open representative gene

PFAM architecture for HKOC_1664347

Simplified PFAM architecture for HKOC_1664347

PFAM domain coverage: 168 / 475 aa (35.4%)

1 aa475 aa

HisKAHATPase_c

Simplified architecture: HisKA + HATPase_c
Raw architecture: HisKA[251-313] | HATPase_c[365-469]
Domain count: 2
Matched identifier: HKOC_1664347
Positioned domains: HisKA 251-313 ; HATPase_c 365-469

Cluster members and taxonomy

Representative gene: GCF_000009245#FTL_RS09010

Sankey plot built from the taxonomy of all members in the selected cluster.

Taxonomy Sankey will load when this section is visible.

Genome taxonomy

Francisella tularensis

Taxonomy recordFrancisella tularensisTaxon ID 263 · GCF_009814095

AssemblyASM981409v1 · Contighaploid

Genome composition1 789 751 bp · 32,0% GCGenome size and GC content from the linked genome record.

Signal transduction countsGenes 2 · HK 1 · RR 1CheA 0 · PP 0

Ranked taxonomy7 ranked levels available

SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderThiotrichalesFamilyFrancisellaceaeGenusFrancisella

Lineage path1 lineage nodes

1Unknown

Open genome Search genes in genome Search HK genes NCBI assembly files

Related genes

Preview from the same derived genome key