1 HisKA#1
252-312 aa · 61 aa · 12.8% of protein
Raw token
HisKA:252:0.0000000000000889:312:61:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
FTL_RS09010
Histidine kinase, Classic
Francisella tularensis subsp. holarctica LVS · GCF_000009245
ClassHKTypeClassicLength475 aaTM2ValidatedNoCompleteYesContextorphan
Gene IDGCF_000009245#FTL_RS09010Stable P2CS identifier used across views.
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c2 TM helices
Protein length475 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 475 aa (35.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideNot predictedFrom HK/TM SQLite database.
Transmembrane helices16-37 aa · 22 aa · 174-196 aa · 23 aa2 helices reported by HK/TM SQLite database.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa475 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
365-470 aa · 106 aa · 22.3% of protein
Raw token
HATPase_c:365:3.68e-29:470:106:109- Raw architecture: HisKA:252:0.0000000000000889:312:61:64#HATPase_c:365:3.68e-29:470:106:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: HK/TM SQLite database
- TMPRED segments: TM helix 16-37; TM helix 174-196
- Complete: Yes
Protein sequence
On-demand local amino-acid sequence in FASTA format
Protein sequence
On-demand local amino-acid sequence in FASTA format
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000009245::NC_007880.1::G00002
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1695821-1697248Genomic interval covered by the local TCS group.
Identifiers
Old locus tagFTL_1762RefSeq proteinWP_003017277.1
Context group ID
GCF_000009245::NC_007880.1::G00002Context members
FTL_RS09010
Partner locus tags
FTL_RS09010
Partner old locus tags
FTL_1762
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003017277.1Primary protein accession used for annex mappings.
UniProt accessionA0AAI8FTV0Primary UniProt accession resolved in the annex database.
UniProt IDA0AAI8FTV0_FRATHDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagFTL_RS09010Primary locus identifier stored in the genes table.
Old locus tagFTL_1762Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_007880.1Sequence record reported by the local genomic context database.
Genomic interval1 695 821-1 697 248 nt1 428 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 695 821-1 697 248 ntGCF_000009245::NC_007880.1::G00002
Quick actions
Genome neighborhood
Gene-centered window parsed directly from the configured gzipped GFF annotation
GCF_000009245 · NC_007880.1Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Centered locusFTL_RS0901011 genes displayed around the current focus.
Configured flank5 upstream / downstreamWindow size loaded from config.ini.
Annotation sourceGCF_000009245.gff.gzResolved as <gff_root_dir>/<genome_id>/<genome_id>.gff.gz when available.
View modeGene-centered orderThis track keeps the current gene in the middle of the context window when possible.
Gene-centered contextFive upstream and five downstream genes can be shown when the configured flank count is set to 5.
Current geneHKRROther P2CSOutside P2CS
1
FTL_RS08980FTL_RS08980
2
FTL_RS10680FTL_RS10680
3
FTL_RS12135FTL_RS12135
4
FTL_RS09000FTL_RS09000
5
FTL_RS09005FTL_RS09005
7
FTL_RS09015FTL_RS09015
8
FTL_RS09025FTL_RS09025
9
FTL_RS09030FTL_RS09030
10
FTL_RS09035FTL_RS09035
11
FTL_RS11675FTL_RS11675
Neighborhood gene cards
11 genes in the current genome window.
FTL_RS08980FTL_RS08980
Outside P2CS
1 690 130-1 691 662 nt · 1 533 nt · Reverse (-)
glycerol-3-phosphate dehydrogenase/oxidase
FTL_RS10680FTL_RS10680
Outside P2CS
1 691 978-1 692 858 nt · 881 nt · Forward (+)
IS630 family transposase
FTL_RS12135FTL_RS12135
Outside P2CS
1 692 836-1 692 994 nt · 159 nt · Reverse (-)
hypothetical protein
FTL_RS09000FTL_RS09000
Outside P2CS
1 693 508-1 694 788 nt · 1 281 nt · Reverse (-)
ATP-grasp domain-containing protein
FTL_RS09005FTL_RS09005
Outside P2CS
1 694 792-1 695 724 nt · 933 nt · Reverse (-)
hypothetical protein
FTL_RS09010FTL_RS09010
HKClassicCurrent focus
1 695 821-1 697 248 nt · 1 428 nt · Forward (+)
sensor histidine kinase
FTL_RS09015FTL_RS09015
Outside P2CS
1 697 245-1 698 126 nt · 882 nt · Reverse (-)
TIGR01777 family oxidoreductase
FTL_RS09025FTL_RS09025
Outside P2CS
1 698 362-1 699 738 nt · 1 377 nt · Forward (+)
cytochrome ubiquinol oxidase subunit I
FTL_RS09030FTL_RS09030
Outside P2CS
1 699 742-1 700 704 nt · 963 nt · Forward (+)
cytochrome d ubiquinol oxidase subunit II
FTL_RS09035FTL_RS09035
Outside P2CS
1 700 715-1 701 149 nt · 435 nt · Forward (+)
DUF3429 domain-containing protein
FTL_RS11675FTL_RS11675
Outside P2CS
1 701 158-1 701 430 nt · 273 nt · Forward (+)
NAD(P)-binding protein
3D Structure
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009245#FTL_RS09010The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1664347
Simplified PFAM architecture for HKOC_1664347
PFAM domain coverage: 168 / 475 aa (35.4%)
1 aa475 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[251-313] | HATPase_c[365-469]
- Domain count: 2
- Matched identifier: HKOC_1664347
- Positioned domains: HisKA 251-313 ; HATPase_c 365-469
Cluster members and taxonomy
Representative gene: GCF_000009245#FTL_RS09010
Sankey plot built from the taxonomy of all members in the selected cluster.
Taxonomy Sankey will load when this section is visible.
Genome taxonomy
Francisella tularensis subsp. holarctica LVS
Taxonomy recordFrancisella tularensis subsp. holarctica LVSTaxon ID 376 619 · GCF_000009245
AssemblyASM924v1 · Complete Genomehaploid
Genome composition1 895 994 bp · 32,0% GCGenome size and GC content from the linked genome record.
Signal transduction countsGenes 2 · HK 1 · RR 1CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderThiotrichalesFamilyFrancisellaceaeGenusFrancisella
Lineage path1 lineage nodes
1Unknown
Related genes
Preview from the same derived genome key