Gene detail

DXD06_RS05635

Histidine kinase, Classic

Roseburia sp. TF10-5 · GCF_003462365

ClassHKTypeClassicLength495 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_003462365#DXD06_RS05635Stable P2CS identifier used across views.
GenomeGCF_003462365Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Selected clusterHKOC_1505473Run 6 · 3 sequences · id 100% · cov 80% · representative
External referencesWP_117830966.1 · MIST4 DXD06_RS05635RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length495 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage250 / 495 aa (50.5%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa495 aa
HAMP: 199-267 aa (69 aa)1His_kinase: 283-360 aa (78 aa)2HATPase_c: 382-484 aa (103 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
199-267 aa · 69 aa · 13.9% of protein
Raw tokenHAMP:199:0.00000000000000662:267:69:69
2 His_kinase#2
283-360 aa · 78 aa · 15.8% of protein
Raw tokenHis_kinase:283:8.08e-31:360:78:80
3 HATPase_c#3
382-484 aa · 103 aa · 20.8% of protein
Raw tokenHATPase_c:382:0.000000000000371:484:105:109
  • Raw architecture: HAMP:199:0.00000000000000662:267:69:69#His_kinase:283:8.08e-31:360:78:80#HATPase_c:382:0.000000000000371:484:105:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_003462365::NZ_QTYW01000004.1::G00046
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span85103-86590Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDXD06_05640RefSeq proteinWP_117830966.1
Context group IDGCF_003462365::NZ_QTYW01000004.1::G00046
Context members
DXD06_RS05635
Partner locus tags
DXD06_RS05635
Partner old locus tags
DXD06_05640
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_117830966.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDXD06_RS05635Primary locus identifier stored in the genes table.
Old locus tagDXD06_05640Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QTYW01000004.1Sequence record reported by the local genomic context database.
Genomic interval85 103-86 590 nt1 488 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span85 103-86 590 ntGCF_003462365::NZ_QTYW01000004.1::G00046

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003462365::NZ_QTYW01000004.1::G00046

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QTYW01000004.1All displayed genes belong to this local TCS context.
Neighborhood span85 103-86 590 nt1 488 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
85 103 nt86 590 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

DXD06_RS05635GCF_003462365#DXD06_RS05635
HKClassicCurrent focus

85 103-86 590 nt · Forward (+)

Old locus DXD06_05640RefSeq WP_117830966.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1505473Run 6 · HK · 3 sequences
Representative sequenceGCF_003462365#DXD06_RS05635The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1505473

Simplified PFAM architecture for HKOC_1505473

PFAM domain coverage: 234 / 495 aa (47.3%)

1 aa495 aa
HAMP: 217-267 aaHAMPHis_kinase: 283-360 aaHis_kinaseHATPase_c: 381-485 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[217-267] | His_kinase[283-360] | HATPase_c[381-485]
  • Domain count: 3
  • Matched identifier: HKOC_1505473
  • Positioned domains: HAMP 217-267 ; His_kinase 283-360 ; HATPase_c 381-485
Cluster members and taxonomy
Visualization

Representative gene: GCF_003462365#DXD06_RS05635

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 293 144 · GCF_003462365
AssemblyASM346236v1 · Scaffoldhaploid
Genome composition3 443 473 bp · 43,0% GCRoseburia sp. TF10-5
Signal transduction countsGenes 112 · HK 50 · RR 61CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia

Related genes

Preview from the same derived genome key