Gene detail

DXD06_RS00375

Histidine kinase, CheA

Roseburia sp. TF10-5 · GCF_003462365

ClassHKTypeCheALength698 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003462365#DXD06_RS00375Stable P2CS identifier used across views.
GenomeGCF_003462365Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Selected clusterHKOC_0773614Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_117830256.1 · MIST4 DXD06_RS00375RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HptH-kinase_dimHATPase_cCheW
Protein length698 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage425 / 698 aa (60.9%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa698 aa
Hpt: 5-97 aa (93 aa)1H-kinase_dim: 316-379 aa (64 aa)2HATPase_c: 427-566 aa (140 aa)3CheW: 571-698 aa (128 aa)4
Domain-by-domain annotation4 items
1 Hpt#1
5-97 aa · 93 aa · 13.3% of protein
Raw tokenHpt:5:1.68e-17:97:93:84
2 H-kinase_dim#2
316-379 aa · 64 aa · 9.2% of protein
Raw tokenH-kinase_dim:316:6.74e-16:379:67:67
3 HATPase_c#3
427-566 aa · 140 aa · 20.1% of protein
Raw tokenHATPase_c:427:0.00000000000000104:566:140:109
4 CheW#4
571-698 aa · 128 aa · 18.3% of protein
Raw tokenCheW:571:2.84e-30:698:135:138
  • Raw architecture: Hpt:5:1.68e-17:97:93:84#H-kinase_dim:316:6.74e-16:379:67:67#HATPase_c:427:0.00000000000000104:566:140:109#CheW:571:2.84e-30:698:135:138
  • Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003462365::NZ_QTYW01000001.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span71476-74638Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDXD06_00375RefSeq proteinWP_117830256.1
Context group IDGCF_003462365::NZ_QTYW01000001.1::G00001
Context members
DXD06_RS00370DXD06_RS00375
Partner locus tags
DXD06_RS00370DXD06_RS00375
Partner old locus tags
DXD06_00370DXD06_00375
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_117830256.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDXD06_RS00375Primary locus identifier stored in the genes table.
Old locus tagDXD06_00375Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QTYW01000001.1Sequence record reported by the local genomic context database.
Genomic interval72 542-74 638 nt2 097 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span71 476-74 638 ntGCF_003462365::NZ_QTYW01000001.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003462365::NZ_QTYW01000001.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QTYW01000001.1All displayed genes belong to this local TCS context.
Neighborhood span71 476-74 638 nt3 163 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
71 476 nt74 638 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DXD06_RS00370GCF_003462365#DXD06_RS00370
RRCheB

71 476-72 540 nt · Forward (+)

Old locus DXD06_00370RefSeq WP_055263833.1
DXD06_RS00375GCF_003462365#DXD06_RS00375
HKCheACurrent focus

72 542-74 638 nt · Forward (+)

Old locus DXD06_00375RefSeq WP_117830256.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0773614Run 6 · HK · 1 sequences
Representative sequenceGCF_003462365#DXD06_RS00375The current gene is the representative for this cluster.
PFAM architectureHpt + P2 + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0773614

Simplified PFAM architecture for HKOC_0773614

PFAM domain coverage: 500 / 698 aa (71.6%)

1 aa698 aa
Hpt: 5-97 aaHptP2: 182-257 aaP2H-kinase_dim: 315-379 aaH-kinase_dimHATPase_c: 428-566 aaHATPase_cCheW: 571-697 aaCheW
HptP2H-kinase_dimHATPase_cCheW
  • Simplified architecture: Hpt + P2 + H-kinase_dim + HATPase_c + CheW
  • Raw architecture: Hpt[5-97] | P2[182-257] | H-kinase_dim[315-379] | HATPase_c[428-566] | CheW[571-697]
  • Domain count: 5
  • Matched identifier: HKOC_0773614
  • Positioned domains: Hpt 5-97 ; P2 182-257 ; H-kinase_dim 315-379 ; HATPase_c 428-566 ; CheW 571-697
Cluster members and taxonomy
Visualization

Representative gene: GCF_003462365#DXD06_RS00375

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 293 144 · GCF_003462365
AssemblyASM346236v1 · Scaffoldhaploid
Genome composition3 443 473 bp · 43,0% GCRoseburia sp. TF10-5
Signal transduction countsGenes 112 · HK 50 · RR 61CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia

Related genes

Preview from the same derived genome key