Gene detail

DXD06_RS03665

Histidine kinase, Classic

Roseburia sp. TF10-5 · GCF_003462365

ClassHKTypeClassicLength601 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003462365#DXD06_RS03665Stable P2CS identifier used across views.
GenomeGCF_003462365Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Selected clusterHKOC_1048743Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_117830698.1 · MIST4 DXD06_RS03665RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length601 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage446 / 601 aa (74.2%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa601 aa
dCache_1: 82-278 aa (197 aa)1HAMP: 297-358 aa (62 aa)2His_kinase: 380-459 aa (80 aa)3HATPase_c: 475-581 aa (107 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
82-278 aa · 197 aa · 32.8% of protein
Raw tokendCache_1:82:0.0000000044:278:206:195
2 HAMP#2
297-358 aa · 62 aa · 10.3% of protein
Raw tokenHAMP:297:0.0000479:358:62:69
3 His_kinase#3
380-459 aa · 80 aa · 13.3% of protein
Raw tokenHis_kinase:380:7.75e-34:459:80:80
4 HATPase_c#4
475-581 aa · 107 aa · 17.8% of protein
Raw tokenHATPase_c:475:6.76e-17:581:110:109
  • Raw architecture: dCache_1:82:0.0000000044:278:206:195#HAMP:297:0.0000479:358:62:69#His_kinase:380:7.75e-34:459:80:80#HATPase_c:475:6.76e-17:581:110:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003462365::NZ_QTYW01000003.1::G00031
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4905-8295Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDXD06_03670RefSeq proteinWP_117830698.1
Context group IDGCF_003462365::NZ_QTYW01000003.1::G00031
Context members
DXD06_RS03660DXD06_RS03665
Partner locus tags
DXD06_RS03660DXD06_RS03665
Partner old locus tags
DXD06_03665DXD06_03670
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_117830698.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDXD06_RS03665Primary locus identifier stored in the genes table.
Old locus tagDXD06_03670Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QTYW01000003.1Sequence record reported by the local genomic context database.
Genomic interval6 490-8 295 nt1 806 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 905-8 295 ntGCF_003462365::NZ_QTYW01000003.1::G00031

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003462365::NZ_QTYW01000003.1::G00031

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QTYW01000003.1All displayed genes belong to this local TCS context.
Neighborhood span4 905-8 295 nt3 391 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 905 nt8 295 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DXD06_RS03660GCF_003462365#DXD06_RS03660
RRunclassified

4 905-6 509 nt · Forward (+)

Old locus DXD06_03665RefSeq WP_117830697.1
DXD06_RS03665GCF_003462365#DXD06_RS03665
HKClassicCurrent focus

6 490-8 295 nt · Forward (+)

Old locus DXD06_03670RefSeq WP_117830698.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1048743Run 6 · HK · 1 sequences
Representative sequenceGCF_003462365#DXD06_RS03665The current gene is the representative for this cluster.
PFAM architecturedCache_1 + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1048743

Simplified PFAM architecture for HKOC_1048743

PFAM domain coverage: 396 / 601 aa (65.9%)

1 aa601 aa
dCache_1: 48-259 aadCache_1His_kinase: 381-459 aaHis_kinaseHATPase_c: 477-581 aaHATPase_c
dCache_1His_kinaseHATPase_c
  • Simplified architecture: dCache_1 + His_kinase + HATPase_c
  • Raw architecture: dCache_1[48-259] | His_kinase[381-459] | HATPase_c[477-581]
  • Domain count: 3
  • Matched identifier: HKOC_1048743
  • Positioned domains: dCache_1 48-259 ; His_kinase 381-459 ; HATPase_c 477-581
Cluster members and taxonomy
Visualization

Representative gene: GCF_003462365#DXD06_RS03665

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 293 144 · GCF_003462365
AssemblyASM346236v1 · Scaffoldhaploid
Genome composition3 443 473 bp · 43,0% GCRoseburia sp. TF10-5
Signal transduction countsGenes 112 · HK 50 · RR 61CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia

Related genes

Preview from the same derived genome key