1 His_kinase#1
372-450 aa · 79 aa · 13.9% of protein
Raw token
His_kinase:372:6.27e-36:450:80:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DWY33_RS00995
Histidine kinase, Classic
Dorea formicigenerans · GCF_003458475
ClassHKTypeClassicLength570 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003458475#DWY33_RS00995Stable P2CS identifier used across views.
GenomeGCF_003458475Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Dorea
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length570 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage177 / 570 aa (31.1%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa570 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
466-563 aa · 98 aa · 17.2% of protein
Raw token
HATPase_c:466:0.00000000000179:563:106:109- Raw architecture: His_kinase:372:6.27e-36:450:80:80#HATPase_c:466:0.00000000000179:563:106:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003458475::NZ_QRUK01000001.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span235791-238246Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDWY33_00995RefSeq proteinWP_243000441.1
Context group ID
GCF_003458475::NZ_QRUK01000001.1::G00003Context members
DWY33_RS00995DWY33_RS01000
Partner locus tags
DWY33_RS00995DWY33_RS01000
Partner old locus tags
DWY33_00995DWY33_01000
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_243000441.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDWY33_RS00995Primary locus identifier stored in the genes table.
Old locus tagDWY33_00995Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QRUK01000001.1Sequence record reported by the local genomic context database.
Genomic interval235 791-237 503 nt1 713 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span235 791-238 246 ntGCF_003458475::NZ_QRUK01000001.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003458475::NZ_QRUK01000001.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QRUK01000001.1All displayed genes belong to this local TCS context.
Neighborhood span235 791-238 246 nt2 456 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
235 791 nt238 246 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DWY33_RS00995GCF_003458475#DWY33_RS00995
HKClassicCurrent focus
235 791-237 503 nt · Forward (+)
DWY33_RS01000GCF_003458475#DWY33_RS01000
RRLytTR
237 500-238 246 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_003458475#DWY33_RS00995The current gene is the representative for this cluster.
PFAM architecture5TM-5TMR_LYT + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1212919
Simplified PFAM architecture for HKOC_1212919
PFAM domain coverage: 338 / 570 aa (59.3%)
1 aa570 aa
5TM-5TMR_LYTHis_kinaseHATPase_c
- Simplified architecture: 5TM-5TMR_LYT + His_kinase + HATPase_c
- Raw architecture: 5TM-5TMR_LYT[29-190] | His_kinase[372-450] | HATPase_c[467-563]
- Domain count: 3
- Matched identifier: HKOC_1212919
- Positioned domains: 5TM-5TMR_LYT 29-190 ; His_kinase 372-450 ; HATPase_c 467-563
Cluster members and taxonomy
Representative gene: GCF_003458475#DWY33_RS00995
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 39 486 · GCF_003458475
AssemblyASM345847v1 · Scaffoldhaploid
Genome composition3 302 668 bp · 40,5% GCDorea formicigenerans
Signal transduction countsGenes 95 · HK 53 · RR 40CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusDorea
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Dorea
Related genes
Preview from the same derived genome key