Gene detail

DWY33_RS02355

Histidine kinase, Classic

Dorea formicigenerans · GCF_003458475

ClassHKTypeClassicLength556 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003458475#DWY33_RS02355Stable P2CS identifier used across views.
GenomeGCF_003458475Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Dorea
Selected clusterHKOC_1100575Run 6 · 9 sequences · id 100% · cov 80%
External referencesWP_243000459.1 · MIST4 DWY33_RS02355RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length556 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage263 / 556 aa (47.3%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa556 aa
HAMP: 258-327 aa (70 aa)1His_kinase: 342-421 aa (80 aa)2HATPase_c: 437-549 aa (113 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
258-327 aa · 70 aa · 12.6% of protein
Raw tokenHAMP:258:0.000000000000104:327:70:69
2 His_kinase#2
342-421 aa · 80 aa · 14.4% of protein
Raw tokenHis_kinase:342:2.95e-33:421:80:80
3 HATPase_c#3
437-549 aa · 113 aa · 20.3% of protein
Raw tokenHATPase_c:437:0.000000000836:549:114:109
  • Raw architecture: HAMP:258:0.000000000000104:327:70:69#His_kinase:342:2.95e-33:421:80:80#HATPase_c:437:0.000000000836:549:114:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003458475::NZ_QRUK01000002.1::G00021
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span233792-237195Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDWY33_02355RefSeq proteinWP_243000459.1
Context group IDGCF_003458475::NZ_QRUK01000002.1::G00021
Context members
DWY33_RS02355DWY33_RS02360
Partner locus tags
DWY33_RS02355DWY33_RS02360
Partner old locus tags
DWY33_02355DWY33_02360
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_243000459.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDWY33_RS02355Primary locus identifier stored in the genes table.
Old locus tagDWY33_02355Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QRUK01000002.1Sequence record reported by the local genomic context database.
Genomic interval233 792-235 462 nt1 671 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span233 792-237 195 ntGCF_003458475::NZ_QRUK01000002.1::G00021

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003458475::NZ_QRUK01000002.1::G00021

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QRUK01000002.1All displayed genes belong to this local TCS context.
Neighborhood span233 792-237 195 nt3 404 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
233 792 nt237 195 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DWY33_RS02355GCF_003458475#DWY33_RS02355
HKClassicCurrent focus

233 792-235 462 nt · Reverse (-)

Old locus DWY33_02355RefSeq WP_243000459.1
DWY33_RS02360GCF_003458475#DWY33_RS02360
RRunclassified

235 567-237 195 nt · Reverse (-)

Old locus DWY33_02360RefSeq WP_118397223.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1100575Run 6 · HK · 9 sequences
Representative sequenceGCF_003436235#DXD84_RS02265Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1100575

Simplified PFAM architecture for HKOC_1100575

PFAM domain coverage: 245 / 592 aa (41.4%)

1 aa592 aa
HAMP: 311-363 aaHAMPHis_kinase: 379-455 aaHis_kinaseHATPase_c: 472-586 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[311-363] | His_kinase[379-455] | HATPase_c[472-586]
  • Domain count: 3
  • Matched identifier: HKOC_1100575
  • Positioned domains: HAMP 311-363 ; His_kinase 379-455 ; HATPase_c 472-586
Cluster members and taxonomy
Visualization

Representative gene: GCF_003436235#DXD84_RS02265

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 39 486 · GCF_003458475
AssemblyASM345847v1 · Scaffoldhaploid
Genome composition3 302 668 bp · 40,5% GCDorea formicigenerans
Signal transduction countsGenes 95 · HK 53 · RR 40CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusDorea
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Dorea

Related genes

Preview from the same derived genome key