Gene detail

DWZ12_RS08365

Histidine kinase, Classic

Blautia obeum · GCF_003457595

ClassHKTypeClassicLength499 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003457595#DWZ12_RS08365Stable P2CS identifier used across views.
GenomeGCF_003457595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1482547Run 6 · 21 sequences · id 100% · cov 80% · representative
External referencesWP_117591885.1 · A0A395ZZB0 · MIST4 DWZ12_RS08365RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length499 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage258 / 499 aa (51.7%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa499 aa
HAMP: 190-259 aa (70 aa)1His_kinase: 288-367 aa (80 aa)2HATPase_c: 386-493 aa (108 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
190-259 aa · 70 aa · 14.0% of protein
Raw tokenHAMP:190:0.000000000000172:259:70:69
2 His_kinase#2
288-367 aa · 80 aa · 16.0% of protein
Raw tokenHis_kinase:288:2.41e-26:367:80:80
3 HATPase_c#3
386-493 aa · 108 aa · 21.6% of protein
Raw tokenHATPase_c:386:0.0000000000000918:493:111:109
  • Raw architecture: HAMP:190:0.000000000000172:259:70:69#His_kinase:288:2.41e-26:367:80:80#HATPase_c:386:0.0000000000000918:493:111:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003457595::NZ_QRSS01000008.1::G00046
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span21777-24914Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDWZ12_08365RefSeq proteinWP_117591885.1
Context group IDGCF_003457595::NZ_QRSS01000008.1::G00046
Context members
DWZ12_RS08360DWZ12_RS08365
Partner locus tags
DWZ12_RS08360DWZ12_RS08365
Partner old locus tags
DWZ12_08360DWZ12_08365
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_117591885.1Primary protein accession used for annex mappings.
UniProt accessionA0A395ZZB0Primary UniProt accession resolved in the annex database.
UniProt IDA0A395ZZB0_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDWZ12_RS08365Primary locus identifier stored in the genes table.
Old locus tagDWZ12_08365Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QRSS01000008.1Sequence record reported by the local genomic context database.
Genomic interval23 415-24 914 nt1 500 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span21 777-24 914 ntGCF_003457595::NZ_QRSS01000008.1::G00046

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003457595::NZ_QRSS01000008.1::G00046

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QRSS01000008.1All displayed genes belong to this local TCS context.
Neighborhood span21 777-24 914 nt3 138 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
21 777 nt24 914 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DWZ12_RS08360GCF_003457595#DWZ12_RS08360
RRunclassified

21 777-23 372 nt · Reverse (-)

Old locus DWZ12_08360RefSeq WP_055055366.1
DWZ12_RS08365GCF_003457595#DWZ12_RS08365
HKClassicCurrent focus

23 415-24 914 nt · Reverse (-)

Old locus DWZ12_08365RefSeq WP_117591885.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1482547Run 6 · HK · 21 sequences
Representative sequenceGCF_003457595#DWZ12_RS08365The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1482547

Simplified PFAM architecture for HKOC_1482547

PFAM domain coverage: 240 / 499 aa (48.1%)

1 aa499 aa
HAMP: 206-259 aaHAMPHis_kinase: 288-364 aaHis_kinaseHATPase_c: 385-493 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[206-259] | His_kinase[288-364] | HATPase_c[385-493]
  • Domain count: 3
  • Matched identifier: HKOC_1482547
  • Positioned domains: HAMP 206-259 ; His_kinase 288-364 ; HATPase_c 385-493
Cluster members and taxonomy
Visualization

Representative gene: GCF_003457595#DWZ12_RS08365

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 40 520 · GCF_003457595
AssemblyASM345759v1 · Scaffoldhaploid
Genome composition3 533 904 bp · 41,5% GCBlautia obeum
Signal transduction countsGenes 89 · HK 49 · RR 39CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key