Gene detail

DXD81_RS00380

Histidine kinase, Classic

Blautia obeum · GCF_003436075

ClassHKTypeClassicLength604 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003436075#DXD81_RS00380Stable P2CS identifier used across views.
GenomeGCF_003436075Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1033753Run 6 · 11 sequences · id 100% · cov 80% · representative
External referencesWP_117638310.1 · A0A415HSM5 · MIST4 DXD81_RS00380RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length604 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage511 / 604 aa (84.6%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa604 aa
dCache_1: 39-292 aa (254 aa)1HAMP: 307-378 aa (72 aa)2His_kinase: 394-471 aa (78 aa)3HATPase_c: 487-593 aa (107 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
39-292 aa · 254 aa · 42.1% of protein
Raw tokendCache_1:39:0.00000000000347:292:256:195
2 HAMP#2
307-378 aa · 72 aa · 11.9% of protein
Raw tokenHAMP:307:0.000000000000332:378:72:69
3 His_kinase#3
394-471 aa · 78 aa · 12.9% of protein
Raw tokenHis_kinase:394:3.16e-33:471:79:80
4 HATPase_c#4
487-593 aa · 107 aa · 17.7% of protein
Raw tokenHATPase_c:487:0.00000000000000182:593:109:109
  • Raw architecture: dCache_1:39:0.00000000000347:292:256:195#HAMP:307:0.000000000000332:378:72:69#His_kinase:394:3.16e-33:471:79:80#HATPase_c:487:0.00000000000000182:593:109:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003436075::NZ_QSOL01000001.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span87438-90839Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDXD81_00380RefSeq proteinWP_117638310.1
Context group IDGCF_003436075::NZ_QSOL01000001.1::G00004
Context members
DXD81_RS00375DXD81_RS00380
Partner locus tags
DXD81_RS00375DXD81_RS00380
Partner old locus tags
DXD81_00375DXD81_00380
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_117638310.1Primary protein accession used for annex mappings.
UniProt accessionA0A415HSM5Primary UniProt accession resolved in the annex database.
UniProt IDA0A415HSM5_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDXD81_RS00380Primary locus identifier stored in the genes table.
Old locus tagDXD81_00380Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QSOL01000001.1Sequence record reported by the local genomic context database.
Genomic interval89 025-90 839 nt1 815 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span87 438-90 839 ntGCF_003436075::NZ_QSOL01000001.1::G00004

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003436075::NZ_QSOL01000001.1::G00004

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QSOL01000001.1All displayed genes belong to this local TCS context.
Neighborhood span87 438-90 839 nt3 402 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
87 438 nt90 839 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DXD81_RS00375GCF_003436075#DXD81_RS00375
RRunclassified

87 438-89 021 nt · Forward (+)

Old locus DXD81_00375RefSeq WP_181975927.1
DXD81_RS00380GCF_003436075#DXD81_RS00380
HKClassicCurrent focus

89 025-90 839 nt · Forward (+)

Old locus DXD81_00380RefSeq WP_117638310.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1033753Run 6 · HK · 11 sequences
Representative sequenceGCF_003436075#DXD81_RS00380The current gene is the representative for this cluster.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1033753

Simplified PFAM architecture for HKOC_1033753

PFAM domain coverage: 477 / 604 aa (79.0%)

1 aa604 aa
dCache_1: 47-290 aadCache_1HAMP: 330-377 aaHAMPHis_kinase: 394-471 aaHis_kinaseHATPase_c: 488-594 aaHATPase_c
dCache_1HAMPHis_kinaseHATPase_c
  • Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
  • Raw architecture: dCache_1[47-290] | HAMP[330-377] | His_kinase[394-471] | HATPase_c[488-594]
  • Domain count: 4
  • Matched identifier: HKOC_1033753
  • Positioned domains: dCache_1 47-290 ; HAMP 330-377 ; His_kinase 394-471 ; HATPase_c 488-594
Cluster members and taxonomy
Visualization

Representative gene: GCF_003436075#DXD81_RS00380

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 40 520 · GCF_003436075
AssemblyASM343607v1 · Scaffoldhaploid
Genome composition3 875 562 bp · 41,5% GCBlautia obeum
Signal transduction countsGenes 115 · HK 61 · RR 53CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key