1 HisKA#1
369-435 aa · 67 aa · 9.3% of protein
Raw token
HisKA:369:0.000000000356:435:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DW677_RS10105
Histidine kinase, Hybrid
Clostridium sp. AM25-23AC · GCF_003435125
ClassHKTypeHybridLength717 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003435125#DW677_RS10105Stable P2CS identifier used across views.
GenomeGCF_003435125Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_cResponse_reg
Protein length717 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage265 / 717 aa (37.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa717 aa
Domain-by-domain annotation3 items
2 HATPase_c#2
477-585 aa · 109 aa · 15.2% of protein
Raw token
HATPase_c:477:8.22e-27:585:110:1093 Response_reg#3
628-716 aa · 89 aa · 12.4% of protein
Raw token
Response_reg:628:0.000006:716:90:111- Raw architecture: HisKA:369:0.000000000356:435:67:64#HATPase_c:477:8.22e-27:585:110:109#Response_reg:628:0.000006:716:90:111
- Domain description: 1 HisKA,1 HATPase_c,1 Response_reg
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003435125::NZ_QWGI01000014.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span75901-78756Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW677_10115RefSeq proteinWP_117567110.1
Context group ID
GCF_003435125::NZ_QWGI01000014.1::G00012Context members
DW677_RS10100DW677_RS10105
Partner locus tags
DW677_RS10100DW677_RS10105
Partner old locus tags
DW677_10110DW677_10115
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_117567110.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDW677_RS10105Primary locus identifier stored in the genes table.
Old locus tagDW677_10115Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWGI01000014.1Sequence record reported by the local genomic context database.
Genomic interval76 603-78 756 nt2 154 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span75 901-78 756 ntGCF_003435125::NZ_QWGI01000014.1::G00012
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003435125::NZ_QWGI01000014.1::G00012Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWGI01000014.1All displayed genes belong to this local TCS context.
Neighborhood span75 901-78 756 nt2 856 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
75 901 nt78 756 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DW677_RS10100GCF_003435125#DW677_RS10100
RROmpR
75 901-76 593 nt · Forward (+)
DW677_RS10105GCF_003435125#DW677_RS10105
HKHybridCurrent focus
76 603-78 756 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_003435125#DW677_RS10105The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0738807
Simplified PFAM architecture for HKOC_0738807
PFAM domain coverage: 173 / 717 aa (24.1%)
1 aa717 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[370-435] | HATPase_c[480-586]
- Domain count: 2
- Matched identifier: HKOC_0738807
- Positioned domains: HisKA 370-435 ; HATPase_c 480-586
Cluster members and taxonomy
Representative gene: GCF_003435125#DW677_RS10105
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 2 305 240 · GCF_003435125
AssemblyASM343512v1 · Scaffoldhaploid
Genome composition3 757 782 bp · 48,0% GCClostridium sp. AM25-23AC
Signal transduction countsGenes 66 · HK 30 · RR 34CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium
Related genes
Preview from the same derived genome key