Gene detail

DW677_RS00425

Histidine kinase, Classic

Clostridium sp. AM25-23AC · GCF_003435125

ClassHKTypeClassicLength378 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003435125#DW677_RS00425Stable P2CS identifier used across views.
GenomeGCF_003435125Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Selected clusterHKOC_2628178Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_117566287.1 · MIST4 DW677_RS00425RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length378 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage241 / 378 aa (63.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa378 aa
HAMP: 64-126 aa (63 aa)1HisKA: 144-210 aa (67 aa)2HATPase_c: 256-366 aa (111 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
64-126 aa · 63 aa · 16.7% of protein
Raw tokenHAMP:64:0.0000000781:126:63:69
2 HisKA#2
144-210 aa · 67 aa · 17.7% of protein
Raw tokenHisKA:144:5.92e-18:210:67:64
3 HATPase_c#3
256-366 aa · 111 aa · 29.4% of protein
Raw tokenHATPase_c:256:6.65e-28:366:112:109
  • Raw architecture: HAMP:64:0.0000000781:126:63:69#HisKA:144:5.92e-18:210:67:64#HATPase_c:256:6.65e-28:366:112:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003435125::NZ_QWGI01000001.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span92384-94214Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW677_00425RefSeq proteinWP_117566287.1
Context group IDGCF_003435125::NZ_QWGI01000001.1::G00002
Context members
DW677_RS00425DW677_RS00430
Partner locus tags
DW677_RS00425DW677_RS00430
Partner old locus tags
DW677_00425DW677_00430
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_117566287.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDW677_RS00425Primary locus identifier stored in the genes table.
Old locus tagDW677_00425Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWGI01000001.1Sequence record reported by the local genomic context database.
Genomic interval92 384-93 520 nt1 137 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span92 384-94 214 ntGCF_003435125::NZ_QWGI01000001.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003435125::NZ_QWGI01000001.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWGI01000001.1All displayed genes belong to this local TCS context.
Neighborhood span92 384-94 214 nt1 831 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
92 384 nt94 214 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DW677_RS00425GCF_003435125#DW677_RS00425
HKClassicCurrent focus

92 384-93 520 nt · Reverse (-)

Old locus DW677_00425RefSeq WP_117566287.1
DW677_RS00430GCF_003435125#DW677_RS00430
RROmpR

93 510-94 214 nt · Reverse (-)

Old locus DW677_00430RefSeq WP_015554994.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2628178Run 6 · HK · 1 sequences
Representative sequenceGCF_003435125#DW677_RS00425The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2628178

Simplified PFAM architecture for HKOC_2628178

PFAM domain coverage: 215 / 378 aa (56.9%)

1 aa378 aa
HAMP: 87-126 aaHAMPHisKA: 144-209 aaHisKAHATPase_c: 257-365 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[87-126] | HisKA[144-209] | HATPase_c[257-365]
  • Domain count: 3
  • Matched identifier: HKOC_2628178
  • Positioned domains: HAMP 87-126 ; HisKA 144-209 ; HATPase_c 257-365
Cluster members and taxonomy
Visualization

Representative gene: GCF_003435125#DW677_RS00425

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 305 240 · GCF_003435125
AssemblyASM343512v1 · Scaffoldhaploid
Genome composition3 757 782 bp · 48,0% GCClostridium sp. AM25-23AC
Signal transduction countsGenes 66 · HK 30 · RR 34CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium

Related genes

Preview from the same derived genome key