Gene detail

CUS33_RS13775

Histidine kinase, Classic

Enterococcus faecalis · GCF_002946755

ClassHKTypeClassicLength509 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002946755#CUS33_RS13775Stable P2CS identifier used across views.
GenomeGCF_002946755Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1433404Run 6 · 18 sequences · id 100% · cov 80% · representative
External referencesWP_104855352.1 · MIST4 CUS33_RS13775RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length509 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage250 / 509 aa (49.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa509 aa
HAMP: 195-266 aa (72 aa)1HisKA: 270-336 aa (67 aa)2HATPase_c: 384-494 aa (111 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
195-266 aa · 72 aa · 14.1% of protein
Raw tokenHAMP:195:0.00000000000657:266:72:69
2 HisKA#2
270-336 aa · 67 aa · 13.2% of protein
Raw tokenHisKA:270:0.00000000000000823:336:67:64
3 HATPase_c#3
384-494 aa · 111 aa · 21.8% of protein
Raw tokenHATPase_c:384:7.69e-30:494:111:109
  • Raw architecture: HAMP:195:0.00000000000657:266:72:69#HisKA:270:0.00000000000000823:336:67:64#HATPase_c:384:7.69e-30:494:111:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002946755::NZ_PUBH01000058.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1042-3268Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCUS33_13775RefSeq proteinWP_104855352.1
Context group IDGCF_002946755::NZ_PUBH01000058.1::G00011
Context members
CUS33_RS13775CUS33_RS13780
Partner locus tags
CUS33_RS13775CUS33_RS13780
Partner old locus tags
CUS33_13775CUS33_13780
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_104855352.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCUS33_RS13775Primary locus identifier stored in the genes table.
Old locus tagCUS33_13775Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PUBH01000058.1Sequence record reported by the local genomic context database.
Genomic interval1 042-2 571 nt1 530 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 042-3 268 ntGCF_002946755::NZ_PUBH01000058.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002946755::NZ_PUBH01000058.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PUBH01000058.1All displayed genes belong to this local TCS context.
Neighborhood span1 042-3 268 nt2 227 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 042 nt3 268 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CUS33_RS13775GCF_002946755#CUS33_RS13775
HKClassicCurrent focus

1 042-2 571 nt · Reverse (-)

Old locus CUS33_13775RefSeq WP_104855352.1
CUS33_RS13780GCF_002946755#CUS33_RS13780
RROmpR

2 582-3 268 nt · Reverse (-)

Old locus CUS33_13780RefSeq WP_002355954.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1433404Run 6 · HK · 18 sequences
Representative sequenceGCF_002946755#CUS33_RS13775The current gene is the representative for this cluster.
PFAM architectureArlS_N + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1433404

Simplified PFAM architecture for HKOC_1433404

PFAM domain coverage: 373 / 509 aa (73.3%)

1 aa509 aa
ArlS_N: 45-189 aaArlS_NHAMP: 213-265 aaHAMPHisKA: 271-336 aaHisKAHATPase_c: 385-493 aaHATPase_c
ArlS_NHAMPHisKAHATPase_c
  • Simplified architecture: ArlS_N + HAMP + HisKA + HATPase_c
  • Raw architecture: ArlS_N[45-189] | HAMP[213-265] | HisKA[271-336] | HATPase_c[385-493]
  • Domain count: 4
  • Matched identifier: HKOC_1433404
  • Positioned domains: ArlS_N 45-189 ; HAMP 213-265 ; HisKA 271-336 ; HATPase_c 385-493
Cluster members and taxonomy
Visualization

Representative gene: GCF_002946755#CUS33_RS13775

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 351 · GCF_002946755
AssemblyASM294675v1 · Contighaploid
Genome composition2 775 983 bp · 37,5% GCEnterococcus faecalis
Signal transduction countsGenes 27 · HK 12 · RR 15CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key