1 HAMP#1
288-360 aa · 73 aa · 12.7% of protein
Raw token
HAMP:288:0.0000000876:360:73:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CUS33_RS00300
Histidine kinase, Classic
Enterococcus faecalis · GCF_002946755
ClassHKTypeClassicLength576 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002946755#CUS33_RS00300Stable P2CS identifier used across views.
GenomeGCF_002946755Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length576 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage263 / 576 aa (45.7%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa576 aa
Domain-by-domain annotation3 items
2 His_kinase#2
375-453 aa · 79 aa · 13.7% of protein
Raw token
His_kinase:375:2.53e-27:453:80:803 HATPase_c#3
464-574 aa · 111 aa · 19.3% of protein
Raw token
HATPase_c:464:0.0000000000135:574:113:109- Raw architecture: HAMP:288:0.0000000876:360:73:69#His_kinase:375:2.53e-27:453:80:80#HATPase_c:464:0.0000000000135:574:113:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_002946755::NZ_PUBH01000002.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span5515-8738Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCUS33_00300RefSeq proteinWP_164982880.1
Context group ID
GCF_002946755::NZ_PUBH01000002.1::G00003Context members
CUS33_RS00300CUS33_RS00305
Partner locus tags
CUS33_RS00300CUS33_RS00305
Partner old locus tags
CUS33_00300CUS33_00305
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_164982880.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCUS33_RS00300Primary locus identifier stored in the genes table.
Old locus tagCUS33_00300Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PUBH01000002.1Sequence record reported by the local genomic context database.
Genomic interval5 515-7 245 nt1 731 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span5 515-8 738 ntGCF_002946755::NZ_PUBH01000002.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_002946755::NZ_PUBH01000002.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PUBH01000002.1All displayed genes belong to this local TCS context.
Neighborhood span5 515-8 738 nt3 224 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 515 nt8 738 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
CUS33_RS00300GCF_002946755#CUS33_RS00300
HKClassicCurrent focus
5 515-7 245 nt · Forward (+)
CUS33_RS00305GCF_002946755#CUS33_RS00305
RRunclassified
7 257-8 738 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_002946755#CUS33_RS00300The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1184082
Simplified PFAM architecture for HKOC_1184082
PFAM domain coverage: 180 / 576 aa (31.3%)
1 aa576 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[375-453] | HATPase_c[474-574]
- Domain count: 2
- Matched identifier: HKOC_1184082
- Positioned domains: His_kinase 375-453 ; HATPase_c 474-574
Cluster members and taxonomy
Representative gene: GCF_002946755#CUS33_RS00300
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 351 · GCF_002946755
AssemblyASM294675v1 · Contighaploid
Genome composition2 775 983 bp · 37,5% GCEnterococcus faecalis
Signal transduction countsGenes 27 · HK 12 · RR 15CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key