Gene detail

CUS33_RS02225

Histidine kinase, Classic

Enterococcus faecalis · GCF_002946755

ClassHKTypeClassicLength590 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002946755#CUS33_RS02225Stable P2CS identifier used across views.
GenomeGCF_002946755Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1111088Run 6 · 13 sequences · id 100% · cov 80% · representative
External referencesWP_104853977.1 · MIST4 CUS33_RS02225RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

sCache_likePAS_4HisKAHATPase_c
Protein length590 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage395 / 590 aa (66.9%)Merged over positioned domains only.
Domain description1 sCache_like,1 PAS_4,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa590 aa
sCache_like: 36-155 aa (120 aa)1PAS_4: 256-361 aa (106 aa)2HisKA: 365-428 aa (64 aa)3HATPase_c: 484-588 aa (105 aa)4
Domain-by-domain annotation4 items
1 sCache_like#1
36-155 aa · 120 aa · 20.3% of protein
Raw tokensCache_like:36:0.00000000032:155:121:114
2 PAS_4#2
256-361 aa · 106 aa · 18.0% of protein
Raw tokenPAS_4:256:0.00000000302:361:111:110
3 HisKA#3
365-428 aa · 64 aa · 10.8% of protein
Raw tokenHisKA:365:2.95e-16:428:64:64
4 HATPase_c#4
484-588 aa · 105 aa · 17.8% of protein
Raw tokenHATPase_c:484:2.74e-32:588:105:109
  • Raw architecture: sCache_like:36:0.00000000032:155:121:114#PAS_4:256:0.00000000302:361:111:110#HisKA:365:2.95e-16:428:64:64#HATPase_c:484:2.74e-32:588:105:109
  • Domain description: 1 sCache_like,1 PAS_4,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002946755::NZ_PUBH01000007.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2518-4997Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCUS33_02225RefSeq proteinWP_104853977.1
Context group IDGCF_002946755::NZ_PUBH01000007.1::G00012
Context members
CUS33_RS02220CUS33_RS02225
Partner locus tags
CUS33_RS02220CUS33_RS02225
Partner old locus tags
CUS33_02220CUS33_02225
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_104853977.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCUS33_RS02225Primary locus identifier stored in the genes table.
Old locus tagCUS33_02225Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PUBH01000007.1Sequence record reported by the local genomic context database.
Genomic interval3 225-4 997 nt1 773 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 518-4 997 ntGCF_002946755::NZ_PUBH01000007.1::G00012

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002946755::NZ_PUBH01000007.1::G00012

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PUBH01000007.1All displayed genes belong to this local TCS context.
Neighborhood span2 518-4 997 nt2 480 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 518 nt4 997 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CUS33_RS02220GCF_002946755#CUS33_RS02220
RROmpR

2 518-3 228 nt · Forward (+)

Old locus CUS33_02220RefSeq WP_002360193.1
CUS33_RS02225GCF_002946755#CUS33_RS02225
HKClassicCurrent focus

3 225-4 997 nt · Forward (+)

Old locus CUS33_02225RefSeq WP_104853977.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1111088Run 6 · HK · 13 sequences
Representative sequenceGCF_002946755#CUS33_RS02225The current gene is the representative for this cluster.
PFAM architecturePAS_4 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1111088

Simplified PFAM architecture for HKOC_1111088

PFAM domain coverage: 276 / 590 aa (46.8%)

1 aa590 aa
PAS_4: 256-360 aaPAS_4HisKA: 366-429 aaHisKAHATPase_c: 481-587 aaHATPase_c
PAS_4HisKAHATPase_c
  • Simplified architecture: PAS_4 + HisKA + HATPase_c
  • Raw architecture: PAS_4[256-360] | HisKA[366-429] | HATPase_c[481-587]
  • Domain count: 3
  • Matched identifier: HKOC_1111088
  • Positioned domains: PAS_4 256-360 ; HisKA 366-429 ; HATPase_c 481-587
Cluster members and taxonomy
Visualization

Representative gene: GCF_002946755#CUS33_RS02225

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 351 · GCF_002946755
AssemblyASM294675v1 · Contighaploid
Genome composition2 775 983 bp · 37,5% GCEnterococcus faecalis
Signal transduction countsGenes 27 · HK 12 · RR 15CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key