1 HAMP#1
289-358 aa · 70 aa · 11.6% of protein
Raw token
HAMP:289:0.000000367:358:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
M72_RS00835
Histidine kinase, Classic
Roseburia faecis · GCF_001406815
ClassHKTypeClassicLength606 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001406815#M72_RS00835Stable P2CS identifier used across views.
GenomeGCF_001406815Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length606 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage263 / 606 aa (43.4%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa606 aa
Domain-by-domain annotation3 items
2 His_kinase#2
373-449 aa · 77 aa · 12.7% of protein
Raw token
His_kinase:373:7.26e-28:449:77:803 HATPase_c#3
463-578 aa · 116 aa · 19.1% of protein
Raw token
HATPase_c:463:4.4e-17:578:116:109- Raw architecture: HAMP:289:0.000000367:358:70:69#His_kinase:373:7.26e-28:449:77:80#HATPase_c:463:4.4e-17:578:116:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_001406815::NZ_CVRR01000004.1::G00007
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span72196-74998Genomic interval covered by the local TCS group.
Identifiers
Old locus tagM72_20521RefSeq proteinWP_055066836.1
Context group ID
GCF_001406815::NZ_CVRR01000004.1::G00007Context members
M72_RS00830M72_RS00835
Partner locus tags
M72_RS00830M72_RS00835
Partner old locus tags
M72_20511M72_20521
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_055066836.1Primary protein accession used for annex mappings.
UniProt accessionA0A0M6WAE5Primary UniProt accession resolved in the annex database.
UniProt IDA0A0M6WAE5_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagM72_RS00835Primary locus identifier stored in the genes table.
Old locus tagM72_20521Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CVRR01000004.1Sequence record reported by the local genomic context database.
Genomic interval73 178-74 998 nt1 821 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span72 196-74 998 ntGCF_001406815::NZ_CVRR01000004.1::G00007
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_001406815::NZ_CVRR01000004.1::G00007Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CVRR01000004.1All displayed genes belong to this local TCS context.
Neighborhood span72 196-74 998 nt2 803 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
72 196 nt74 998 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
M72_RS00830GCF_001406815#M72_RS00830
RRunclassified
72 196-73 200 nt · Reverse (-)
M72_RS00835GCF_001406815#M72_RS00835
HKClassicCurrent focus
73 178-74 998 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_001406815#M72_RS00835The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1023699
Simplified PFAM architecture for HKOC_1023699
PFAM domain coverage: 192 / 606 aa (31.7%)
1 aa606 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[373-449] | HATPase_c[463-577]
- Domain count: 2
- Matched identifier: HKOC_1023699
- Positioned domains: His_kinase 373-449 ; HATPase_c 463-577
Cluster members and taxonomy
Representative gene: GCF_001406815#M72_RS00835
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 301 302 · GCF_001406815
AssemblyM72 · Contighaploid
Genome composition3 334 694 bp · 43,0% GCRoseburia faecis
Signal transduction countsGenes 110 · HK 47 · RR 61CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key