Gene detail

ARA50_RS04105

Histidine kinase, Classic

Blautia obeum · GCF_001404535

ClassHKTypeClassicLength595 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_001404535#ARA50_RS04105Stable P2CS identifier used across views.
GenomeGCF_001404535Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1080446Run 6 · 16 sequences · id 100% · cov 80% · representative
External referencesWP_022387932.1 · A0A173ZJQ1 · MIST4 ARA50_RS04105RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length595 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage494 / 595 aa (83.0%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa595 aa
dCache_1: 47-285 aa (239 aa)1HAMP: 305-374 aa (70 aa)2His_kinase: 389-468 aa (80 aa)3HATPase_c: 484-588 aa (105 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
47-285 aa · 239 aa · 40.2% of protein
Raw tokendCache_1:47:2.23e-22:285:244:195
2 HAMP#2
305-374 aa · 70 aa · 11.8% of protein
Raw tokenHAMP:305:2.61e-16:374:70:69
3 His_kinase#3
389-468 aa · 80 aa · 13.4% of protein
Raw tokenHis_kinase:389:9.7e-35:468:80:80
4 HATPase_c#4
484-588 aa · 105 aa · 17.6% of protein
Raw tokenHATPase_c:484:0.00000000000000332:588:109:109
  • Raw architecture: dCache_1:47:2.23e-22:285:244:195#HAMP:305:2.61e-16:374:70:69#His_kinase:389:9.7e-35:468:80:80#HATPase_c:484:0.00000000000000332:588:109:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_001404535::NZ_CYZD01000003.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span83067-86470Genomic interval covered by the local TCS group.
Identifiers
Old locus tagERS852394_00836RefSeq proteinWP_022387932.1
Context group IDGCF_001404535::NZ_CYZD01000003.1::G00005
Context members
ARA50_RS04105ARA50_RS04110
Partner locus tags
ARA50_RS04105ARA50_RS04110
Partner old locus tags
ERS852394_00836ERS852394_00837
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_022387932.1Primary protein accession used for annex mappings.
UniProt accessionA0A173ZJQ1Primary UniProt accession resolved in the annex database.
UniProt IDA0A173ZJQ1_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagARA50_RS04105Primary locus identifier stored in the genes table.
Old locus tagERS852394_00836Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CYZD01000003.1Sequence record reported by the local genomic context database.
Genomic interval83 067-84 854 nt1 788 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span83 067-86 470 ntGCF_001404535::NZ_CYZD01000003.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_001404535::NZ_CYZD01000003.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CYZD01000003.1All displayed genes belong to this local TCS context.
Neighborhood span83 067-86 470 nt3 404 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
83 067 nt86 470 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ARA50_RS04105GCF_001404535#ARA50_RS04105
HKClassicCurrent focus

83 067-84 854 nt · Reverse (-)

Old locus ERS852394_00836RefSeq WP_022387932.1
ARA50_RS04110GCF_001404535#ARA50_RS04110
RRunclassified

84 851-86 470 nt · Reverse (-)

Old locus ERS852394_00837RefSeq WP_055065758.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1080446Run 6 · HK · 16 sequences
Representative sequenceGCF_001404535#ARA50_RS04105The current gene is the representative for this cluster.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1080446

Simplified PFAM architecture for HKOC_1080446

PFAM domain coverage: 475 / 595 aa (79.8%)

1 aa595 aa
dCache_1: 51-285 aadCache_1HAMP: 321-374 aaHAMPHis_kinase: 389-468 aaHis_kinaseHATPase_c: 484-589 aaHATPase_c
dCache_1HAMPHis_kinaseHATPase_c
  • Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
  • Raw architecture: dCache_1[51-285] | HAMP[321-374] | His_kinase[389-468] | HATPase_c[484-589]
  • Domain count: 4
  • Matched identifier: HKOC_1080446
  • Positioned domains: dCache_1 51-285 ; HAMP 321-374 ; His_kinase 389-468 ; HATPase_c 484-589
Cluster members and taxonomy
Visualization

Representative gene: GCF_001404535#ARA50_RS04105

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 40 520 · GCF_001404535
Assembly13414_6#21 · Scaffoldhaploid
Genome composition3 357 012 bp · 41,5% GCBlautia obeum
Signal transduction countsGenes 83 · HK 43 · RR 39CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key