1 dCache_1#1
187-298 aa · 112 aa · 18.3% of protein
Raw token
dCache_1:187:0.00000126:298:116:195P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1548_RS03165
Histidine kinase, Classic
Clostridium sp. KLE 1755 · GCF_000466465
ClassHKTypeClassicLength611 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000466465#HMPREF1548_RS03165Stable P2CS identifier used across views.
GenomeGCF_000466465Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Domain signature
Compact overview inferred from the domain field
dCache_1HAMPHis_kinaseHATPase_c
Protein length611 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage369 / 611 aa (60.4%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa611 aa
Domain-by-domain annotation4 items
2 HAMP#2
318-388 aa · 71 aa · 11.6% of protein
Raw token
HAMP:318:0.00000000000809:388:71:693 His_kinase#3
403-482 aa · 80 aa · 13.1% of protein
Raw token
His_kinase:403:8.31e-33:482:80:804 HATPase_c#4
502-607 aa · 106 aa · 17.3% of protein
Raw token
HATPase_c:502:0.000000000794:607:110:109- Raw architecture: dCache_1:187:0.00000126:298:116:195#HAMP:318:0.00000000000809:388:71:69#His_kinase:403:8.31e-33:482:80:80#HATPase_c:502:0.000000000794:607:110:109
- Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000466465::NZ_KE992659.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span15242-18621Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1548_00293RefSeq proteinWP_021634288.1
Context group ID
GCF_000466465::NZ_KE992659.1::G00030Context members
HMPREF1548_RS03160HMPREF1548_RS03165
Partner locus tags
HMPREF1548_RS03160HMPREF1548_RS03165
Partner old locus tags
HMPREF1548_00292HMPREF1548_00293
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021634288.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1548_RS03165Primary locus identifier stored in the genes table.
Old locus tagHMPREF1548_00293Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KE992659.1Sequence record reported by the local genomic context database.
Genomic interval16 786-18 621 nt1 836 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span15 242-18 621 ntGCF_000466465::NZ_KE992659.1::G00030
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000466465::NZ_KE992659.1::G00030Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KE992659.1All displayed genes belong to this local TCS context.
Neighborhood span15 242-18 621 nt3 380 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
15 242 nt18 621 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1548_RS03160GCF_000466465#HMPREF1548_RS03160
RRunclassified
15 242-16 771 nt · Forward (+)
HMPREF1548_RS03165GCF_000466465#HMPREF1548_RS03165
HKClassicCurrent focus
16 786-18 621 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000466465#HMPREF1548_RS03165The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1000883
Simplified PFAM architecture for HKOC_1000883
PFAM domain coverage: 185 / 611 aa (30.3%)
1 aa611 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[403-481] | HATPase_c[501-606]
- Domain count: 2
- Matched identifier: HKOC_1000883
- Positioned domains: His_kinase 403-481 ; HATPase_c 501-606
Cluster members and taxonomy
Representative gene: GCF_000466465#HMPREF1548_RS03165
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 226 325 · GCF_000466465
AssemblyASM46646v2 · Scaffoldhaploid
Genome composition6 640 751 bp · 48,0% GCClostridium sp. KLE 1755
Signal transduction countsGenes 300 · HK 152 · RR 145CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium
Related genes
Preview from the same derived genome key