1 HAMP#1
293-362 aa · 70 aa · 12.0% of protein
Raw token
HAMP:293:0.000000000463:362:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1548_RS01090
Histidine kinase, Classic
Clostridium sp. KLE 1755 · GCF_000466465
ClassHKTypeClassicLength582 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000466465#HMPREF1548_RS01090Stable P2CS identifier used across views.
GenomeGCF_000466465Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length582 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage258 / 582 aa (44.3%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa582 aa
Domain-by-domain annotation3 items
2 His_kinase#2
377-457 aa · 81 aa · 13.9% of protein
Raw token
His_kinase:377:7.21e-29:457:81:803 HATPase_c#3
474-580 aa · 107 aa · 18.4% of protein
Raw token
HATPase_c:474:0.00000141:580:108:109- Raw architecture: HAMP:293:0.000000000463:362:70:69#His_kinase:377:7.21e-29:457:81:80#HATPase_c:474:0.00000141:580:108:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000466465::NZ_KE992647.1::G00004
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span4781-6529Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1548_01873RefSeq proteinWP_021633789.1
Context group ID
GCF_000466465::NZ_KE992647.1::G00004Context members
HMPREF1548_RS01090
Partner locus tags
HMPREF1548_RS01090
Partner old locus tags
HMPREF1548_01873
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021633789.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1548_RS01090Primary locus identifier stored in the genes table.
Old locus tagHMPREF1548_01873Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KE992647.1Sequence record reported by the local genomic context database.
Genomic interval4 781-6 529 nt1 749 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 781-6 529 ntGCF_000466465::NZ_KE992647.1::G00004
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000466465::NZ_KE992647.1::G00004Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KE992647.1All displayed genes belong to this local TCS context.
Neighborhood span4 781-6 529 nt1 749 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 781 nt6 529 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
HMPREF1548_RS01090GCF_000466465#HMPREF1548_RS01090
HKClassicCurrent focus
4 781-6 529 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000466465#HMPREF1548_RS01090The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1152590
Simplified PFAM architecture for HKOC_1152590
PFAM domain coverage: 133 / 582 aa (22.9%)
1 aa582 aa
HAMPHis_kinase
- Simplified architecture: HAMP + His_kinase
- Raw architecture: HAMP[309-361] | His_kinase[378-457]
- Domain count: 2
- Matched identifier: HKOC_1152590
- Positioned domains: HAMP 309-361 ; His_kinase 378-457
Cluster members and taxonomy
Representative gene: GCF_000466465#HMPREF1548_RS01090
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 226 325 · GCF_000466465
AssemblyASM46646v2 · Scaffoldhaploid
Genome composition6 640 751 bp · 48,0% GCClostridium sp. KLE 1755
Signal transduction countsGenes 300 · HK 152 · RR 145CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium
Related genes
Preview from the same derived genome key