1 dCache_1#1
40-284 aa · 245 aa · 41.2% of protein
Raw token
dCache_1:40:0.0000204:284:249:195P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1548_RS00555
Histidine kinase, Classic
Clostridium sp. KLE 1755 · GCF_000466465
ClassHKTypeClassicLength595 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000466465#HMPREF1548_RS00555Stable P2CS identifier used across views.
GenomeGCF_000466465Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Domain signature
Compact overview inferred from the domain field
dCache_1HAMPHis_kinaseHATPase_c
Protein length595 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage507 / 595 aa (85.2%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa595 aa
Domain-by-domain annotation4 items
2 HAMP#2
300-375 aa · 76 aa · 12.8% of protein
Raw token
HAMP:300:0.00000000145:375:76:693 His_kinase#3
390-469 aa · 80 aa · 13.4% of protein
Raw token
His_kinase:390:1.24e-30:469:80:804 HATPase_c#4
488-593 aa · 106 aa · 17.8% of protein
Raw token
HATPase_c:488:0.00000000000059:593:109:109- Raw architecture: dCache_1:40:0.0000204:284:249:195#HAMP:300:0.00000000145:375:76:69#His_kinase:390:1.24e-30:469:80:80#HATPase_c:488:0.00000000000059:593:109:109
- Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000466465::NZ_KE992641.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span52903-56257Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1548_07004RefSeq proteinWP_021633663.1
Context group ID
GCF_000466465::NZ_KE992641.1::G00001Context members
HMPREF1548_RS00555HMPREF1548_RS00560
Partner locus tags
HMPREF1548_RS00555HMPREF1548_RS00560
Partner old locus tags
HMPREF1548_07004HMPREF1548_07005
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021633663.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1548_RS00555Primary locus identifier stored in the genes table.
Old locus tagHMPREF1548_07004Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KE992641.1Sequence record reported by the local genomic context database.
Genomic interval52 903-54 690 nt1 788 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span52 903-56 257 ntGCF_000466465::NZ_KE992641.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000466465::NZ_KE992641.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KE992641.1All displayed genes belong to this local TCS context.
Neighborhood span52 903-56 257 nt3 355 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
52 903 nt56 257 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1548_RS00555GCF_000466465#HMPREF1548_RS00555
HKClassicCurrent focus
52 903-54 690 nt · Forward (+)
HMPREF1548_RS00560GCF_000466465#HMPREF1548_RS00560
RRunclassified
54 710-56 257 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000466465#HMPREF1548_RS00555The current gene is the representative for this cluster.
PFAM architecturedCache_1 + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1079975
Simplified PFAM architecture for HKOC_1079975
PFAM domain coverage: 413 / 595 aa (69.4%)
1 aa595 aa
dCache_1His_kinaseHATPase_c
- Simplified architecture: dCache_1 + His_kinase + HATPase_c
- Raw architecture: dCache_1[41-268] | His_kinase[390-469] | HATPase_c[488-592]
- Domain count: 3
- Matched identifier: HKOC_1079975
- Positioned domains: dCache_1 41-268 ; His_kinase 390-469 ; HATPase_c 488-592
Cluster members and taxonomy
Representative gene: GCF_000466465#HMPREF1548_RS00555
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 226 325 · GCF_000466465
AssemblyASM46646v2 · Scaffoldhaploid
Genome composition6 640 751 bp · 48,0% GCClostridium sp. KLE 1755
Signal transduction countsGenes 300 · HK 152 · RR 145CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium
Related genes
Preview from the same derived genome key