1 dCache_1#1
32-269 aa · 238 aa · 41.2% of protein
Raw token
dCache_1:32:0.000000116:269:239:195P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1548_RS01390
Histidine kinase, Classic
Clostridium sp. KLE 1755 · GCF_000466465
ClassHKTypeClassicLength578 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000466465#HMPREF1548_RS01390Stable P2CS identifier used across views.
GenomeGCF_000466465Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Domain signature
Compact overview inferred from the domain field
dCache_1HAMPHis_kinaseHATPase_c
Protein length578 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage481 / 578 aa (83.2%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa578 aa
Domain-by-domain annotation4 items
2 HAMP#2
293-357 aa · 65 aa · 11.2% of protein
Raw token
HAMP:293:0.0000000289:357:65:693 His_kinase#3
373-451 aa · 79 aa · 13.7% of protein
Raw token
His_kinase:373:1.02e-31:451:79:804 HATPase_c#4
468-566 aa · 99 aa · 17.1% of protein
Raw token
HATPase_c:468:0.0000000000028:566:106:109- Raw architecture: dCache_1:32:0.000000116:269:239:195#HAMP:293:0.0000000289:357:65:69#His_kinase:373:1.02e-31:451:79:80#HATPase_c:468:0.0000000000028:566:106:109
- Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000466465::NZ_KE992649.1::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span68813-71606Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1548_00168RefSeq proteinWP_035320555.1
Context group ID
GCF_000466465::NZ_KE992649.1::G00008Context members
HMPREF1548_RS01385HMPREF1548_RS01390
Partner locus tags
HMPREF1548_RS01385HMPREF1548_RS01390
Partner old locus tags
HMPREF1548_00167HMPREF1548_00168
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_035320555.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1548_RS01390Primary locus identifier stored in the genes table.
Old locus tagHMPREF1548_00168Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KE992649.1Sequence record reported by the local genomic context database.
Genomic interval69 870-71 606 nt1 737 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span68 813-71 606 ntGCF_000466465::NZ_KE992649.1::G00008
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000466465::NZ_KE992649.1::G00008Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KE992649.1All displayed genes belong to this local TCS context.
Neighborhood span68 813-71 606 nt2 794 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
68 813 nt71 606 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1548_RS01385GCF_000466465#HMPREF1548_RS01385
RRunclassified
68 813-69 838 nt · Reverse (-)
HMPREF1548_RS01390GCF_000466465#HMPREF1548_RS01390
HKClassicCurrent focus
69 870-71 606 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000466465#HMPREF1548_RS01390The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1172505
Simplified PFAM architecture for HKOC_1172505
PFAM domain coverage: 174 / 578 aa (30.1%)
1 aa578 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[374-449] | HATPase_c[469-566]
- Domain count: 2
- Matched identifier: HKOC_1172505
- Positioned domains: His_kinase 374-449 ; HATPase_c 469-566
Cluster members and taxonomy
Representative gene: GCF_000466465#HMPREF1548_RS01390
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 226 325 · GCF_000466465
AssemblyASM46646v2 · Scaffoldhaploid
Genome composition6 640 751 bp · 48,0% GCClostridium sp. KLE 1755
Signal transduction countsGenes 300 · HK 152 · RR 145CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium
Related genes
Preview from the same derived genome key