Gene detail

QAO_RS12500

Histidine kinase, Classic

Clostridioides difficile CD3 · GCF_000448825

ClassHKTypeClassicLength436 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000448825#QAO_RS12500Stable P2CS identifier used across views.
GenomeGCF_000448825Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2032570Run 6 · 146 sequences · id 100% · cov 80%
External referencesWP_009903237.1 · A0AB74Q936 · MIST4 QAO_RS12500RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length436 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 436 aa (36.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa436 aa
HisKA: 218-278 aa (61 aa)1HATPase_c: 334-433 aa (100 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
218-278 aa · 61 aa · 14.0% of protein
Raw tokenHisKA:218:0.0000000000671:278:61:64
2 HATPase_c#2
334-433 aa · 100 aa · 22.9% of protein
Raw tokenHATPase_c:334:8.12e-25:433:100:109
  • Raw architecture: HisKA:218:0.0000000000671:278:61:64#HATPase_c:334:8.12e-25:433:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000448825::NZ_AVGI01000237.1::G00040
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span26032-28043Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQAO_2541RefSeq proteinWP_009903237.1
Context group IDGCF_000448825::NZ_AVGI01000237.1::G00040
Context members
QAO_RS12500QAO_RS12505
Partner locus tags
QAO_RS12500QAO_RS12505
Partner old locus tags
QAO_2541QAO_2542
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009903237.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74Q936Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74Q936_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQAO_RS12500Primary locus identifier stored in the genes table.
Old locus tagQAO_2541Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGI01000237.1Sequence record reported by the local genomic context database.
Genomic interval26 032-27 342 nt1 311 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span26 032-28 043 ntGCF_000448825::NZ_AVGI01000237.1::G00040

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000448825::NZ_AVGI01000237.1::G00040

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGI01000237.1All displayed genes belong to this local TCS context.
Neighborhood span26 032-28 043 nt2 012 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
26 032 nt28 043 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QAO_RS12500GCF_000448825#QAO_RS12500
HKClassicCurrent focus

26 032-27 342 nt · Reverse (-)

Old locus QAO_2541RefSeq WP_009903237.1
QAO_RS12505GCF_000448825#QAO_RS12505
RROmpR

27 336-28 043 nt · Reverse (-)

Old locus QAO_2542RefSeq WP_021359503.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2032570Run 6 · HK · 146 sequences
Representative sequenceGCF_000449985#QIK_RS13790Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2032570

Simplified PFAM architecture for HKOC_2032570

PFAM domain coverage: 166 / 444 aa (37.4%)

1 aa444 aa
HisKA: 225-286 aaHisKAHATPase_c: 338-441 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[225-286] | HATPase_c[338-441]
  • Domain count: 2
  • Matched identifier: HKOC_2032570
  • Positioned domains: HisKA 225-286 ; HATPase_c 338-441
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449985#QIK_RS13790

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 146 total members. Page 1 / 3.

GCF_000449985#QIK_RS13790 (representative)
QIK_RS13790 · HK · Classic
RefSeq: WP_225548891.1
GCF_000009205#CD630_RS13600
CD630_RS13600 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_000155025#UAB_RS0213960
UAB_RS0213960 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_000448825#QAO_RS12500
QAO_RS12500 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_000449045#QCI_RS12815
QCI_RS12815 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_000449785#QGW_RS04390
QGW_RS04390 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_000450125#QK1_RS05810
QK1_RS05810 · HK · Classic
RefSeq: WP_225548891.1
GCF_000450305#QKK_RS13835
QKK_RS13835 · HK · Classic
RefSeq: WP_225548891.1
GCF_000450345#QKO_RS12920
QKO_RS12920 · HK · Classic
RefSeq: WP_225548891.1
GCF_000450385#QKS_RS12810
QKS_RS12810 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_000450465#QM1_RS13460
QM1_RS13460 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_000450685#QMU_RS12685
QMU_RS12685 · HK · Classic
RefSeq: WP_021406485.1
GCF_000451265#QOW_RS13030
QOW_RS13030 · HK · Classic
RefSeq: WP_225548891.1
GCF_000452345#C677_RS12505
C677_RS12505 · HK · Classic
RefSeq: WP_032509604.1
GCF_000632735#BG47_RS14195
BG47_RS14195 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_000828225#SE46_RS01730
SE46_RS01730 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_000828235#SE44_RS02365
SE44_RS02365 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_000828255#SE45_RS03375
SE45_RS03375 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_000828325#NX98_RS02360
NX98_RS02360 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_000932055#CDIF630_RS14000
CDIF630_RS14000 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_000953275#CD630DERM_RS13665
CD630DERM_RS13665 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_001971935#BER45_RS13585
BER45_RS13585 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_002080065#CDIF630erm_RS13885
CDIF630erm_RS13885 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_002082945#A6J96_RS00795
A6J96_RS00795 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_002301905#BGU50_RS00345
BGU50_RS00345 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_002302115#BGU88_RS18285
BGU88_RS18285 · HK · Classic
RefSeq: WP_225548891.1
GCF_002302835#BGV06_RS12270
BGV06_RS12270 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_002303445#BGU62_RS00095
BGU62_RS00095 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_002304265#BGV13_RS17990
BGV13_RS17990 · HK · Classic
RefSeq: WP_032509604.1
GCF_003481965#CDIF29632_RS13225
CDIF29632_RS13225 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_003482065#CDIF28666_RS13370
CDIF28666_RS13370 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_003862885#EGL91_RS03655
EGL91_RS03655 · HK · Classic
RefSeq: WP_225548891.1
GCF_003862975#EGL86_RS05665
EGL86_RS05665 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_003863135#EGM08_RS05930
EGM08_RS05930 · HK · Classic
RefSeq: WP_032509604.1
GCF_004317645#E0Q60_RS09730
E0Q60_RS09730 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_004318405#E0R07_RS14740
E0R07_RS14740 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_004318425#E0Q86_RS05015
E0Q86_RS05015 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_004318585#E0Q83_RS09130
E0Q83_RS09130 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_004318665#E0Q99_RS07280
E0Q99_RS07280 · HK · Classic
RefSeq: WP_131044130.1
GCF_004318805#E0R18_RS03425
E0R18_RS03425 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_004319305#E0R49_RS08280
E0R49_RS08280 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_004319405#E0R48_RS08525
E0R48_RS08525 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_004684465#E5F43_RS08025
E5F43_RS08025 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_004684475#E5F41_RS15945
E5F41_RS15945 · HK · Classic
RefSeq: WP_032509604.1
GCF_004684485#E5F42_RS11935
E5F42_RS11935 · HK · Classic
RefSeq: WP_225548891.1
GCF_004684495#E5F40_RS08060
E5F40_RS08060 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_004684595#E5F35_RS15410
E5F35_RS15410 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936
GCF_007000635#D1N82_RS06645
D1N82_RS06645 · HK · Classic
RefSeq: WP_142792744.1
GCF_007000725#D1N80_RS06570
D1N80_RS06570 · HK · Classic
RefSeq: WP_032509604.1
GCF_007000825#D1N74_RS07575
D1N74_RS07575 · HK · Classic
RefSeq: WP_009903237.1
UniProt: A0AB74Q936

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 252 · GCF_000448825
AssemblyASM44882v2 · Contighaploid
Genome composition4 072 944 bp · 28,0% GCClostridioides difficile CD3
Signal transduction countsGenes 97 · HK 46 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key