1 HisKA#1
214-274 aa · 61 aa · 14.1% of protein
Raw token
HisKA:214:0.0000000000632:274:61:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
C677_RS12505
Histidine kinase, Classic
Clostridioides difficile F601 · GCF_000452345
ClassHKTypeClassicLength432 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000452345#C677_RS12505Stable P2CS identifier used across views.
GenomeGCF_000452345Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length432 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 432 aa (37.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa432 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
330-429 aa · 100 aa · 23.1% of protein
Raw token
HATPase_c:330:8.99e-25:429:100:109- Raw architecture: HisKA:214:0.0000000000632:274:61:64#HATPase_c:330:8.99e-25:429:100:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000452345::NZ_AVNH01000026.1::G00041
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span22170-24181Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC677_2539RefSeq proteinWP_032509604.1
Context group ID
GCF_000452345::NZ_AVNH01000026.1::G00041Context members
C677_RS12505C677_RS12510
Partner locus tags
C677_RS12505C677_RS12510
Partner old locus tags
C677_2539C677_2540
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_032509604.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagC677_RS12505Primary locus identifier stored in the genes table.
Old locus tagC677_2539Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVNH01000026.1Sequence record reported by the local genomic context database.
Genomic interval22 170-23 468 nt1 299 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span22 170-24 181 ntGCF_000452345::NZ_AVNH01000026.1::G00041
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000452345::NZ_AVNH01000026.1::G00041Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVNH01000026.1All displayed genes belong to this local TCS context.
Neighborhood span22 170-24 181 nt2 012 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
22 170 nt24 181 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
C677_RS12505GCF_000452345#C677_RS12505
HKClassicCurrent focus
22 170-23 468 nt · Reverse (-)
C677_RS12510GCF_000452345#C677_RS12510
RROmpR
23 474-24 181 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000449985#QIK_RS13790Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2032570
Simplified PFAM architecture for HKOC_2032570
PFAM domain coverage: 166 / 444 aa (37.4%)
1 aa444 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[225-286] | HATPase_c[338-441]
- Domain count: 2
- Matched identifier: HKOC_2032570
- Positioned domains: HisKA 225-286 ; HATPase_c 338-441
Cluster members and taxonomy
Representative gene: GCF_000449985#QIK_RS13790
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 232 196 · GCF_000452345
AssemblyASM45234v2 · Contighaploid
Genome composition4 103 199 bp · 28,5% GCClostridioides difficile F601
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key