Gene detail

E5F42_RS11935

Histidine kinase, Classic

Clostridioides difficile · GCF_004684485

ClassHKTypeClassicLength444 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004684485#E5F42_RS11935Stable P2CS identifier used across views.
GenomeGCF_004684485Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2032570Run 6 · 146 sequences · id 100% · cov 80%
External referencesWP_225548891.1 · MIST4 E5F42_RS11935RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length444 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 444 aa (36.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa444 aa
HisKA: 226-286 aa (61 aa)1HATPase_c: 342-441 aa (100 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
226-286 aa · 61 aa · 13.7% of protein
Raw tokenHisKA:226:0.0000000000601:286:61:64
2 HATPase_c#2
342-441 aa · 100 aa · 22.5% of protein
Raw tokenHATPase_c:342:6.91e-25:441:100:109
  • Raw architecture: HisKA:226:0.0000000000601:286:61:64#HATPase_c:342:6.91e-25:441:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_004684485::NZ_SRJX01000183.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span15873-17884Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE5F42_11940RefSeq proteinWP_225548891.1
Context group IDGCF_004684485::NZ_SRJX01000183.1::G00016
Context members
E5F42_RS11935E5F42_RS11940
Partner locus tags
E5F42_RS11935E5F42_RS11940
Partner old locus tags
E5F42_11940E5F42_11945
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_225548891.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE5F42_RS11935Primary locus identifier stored in the genes table.
Old locus tagE5F42_11940Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SRJX01000183.1Sequence record reported by the local genomic context database.
Genomic interval15 873-17 207 nt1 335 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span15 873-17 884 ntGCF_004684485::NZ_SRJX01000183.1::G00016

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004684485::NZ_SRJX01000183.1::G00016

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SRJX01000183.1All displayed genes belong to this local TCS context.
Neighborhood span15 873-17 884 nt2 012 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
15 873 nt17 884 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E5F42_RS11935GCF_004684485#E5F42_RS11935
HKClassicCurrent focus

15 873-17 207 nt · Reverse (-)

Old locus E5F42_11940RefSeq WP_225548891.1
E5F42_RS11940GCF_004684485#E5F42_RS11940
RROmpR

17 177-17 884 nt · Reverse (-)

Old locus E5F42_11945RefSeq WP_021359503.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2032570Run 6 · HK · 146 sequences
Representative sequenceGCF_000449985#QIK_RS13790Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2032570

Simplified PFAM architecture for HKOC_2032570

PFAM domain coverage: 166 / 444 aa (37.4%)

1 aa444 aa
HisKA: 225-286 aaHisKAHATPase_c: 338-441 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[225-286] | HATPase_c[338-441]
  • Domain count: 2
  • Matched identifier: HKOC_2032570
  • Positioned domains: HisKA 225-286 ; HATPase_c 338-441
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449985#QIK_RS13790

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004684485
AssemblyASM468448v1 · Contighaploid
Genome composition4 267 338 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key