Gene detail

HMPREF1093_RS18965

Histidine kinase, Classic

Hungatella hathewayi 12489931 · GCF_000371445

ClassHKTypeClassicLength629 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000371445#HMPREF1093_RS18965Stable P2CS identifier used across views.
GenomeGCF_000371445Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella
Selected clusterHKOC_0950770Run 6 · 6 sequences · id 100% · cov 80% · representative
External referencesWP_002603582.1 · MIST4 HMPREF1093_RS18965RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length629 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage370 / 629 aa (58.8%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa629 aa
dCache_1: 193-300 aa (108 aa)1HAMP: 319-389 aa (71 aa)2His_kinase: 405-484 aa (80 aa)3HATPase_c: 504-614 aa (111 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
193-300 aa · 108 aa · 17.2% of protein
Raw tokendCache_1:193:0.000000989:300:112:195
2 HAMP#2
319-389 aa · 71 aa · 11.3% of protein
Raw tokenHAMP:319:0.000000000106:389:71:69
3 His_kinase#3
405-484 aa · 80 aa · 12.7% of protein
Raw tokenHis_kinase:405:1.94e-30:484:80:80
4 HATPase_c#4
504-614 aa · 111 aa · 17.6% of protein
Raw tokenHATPase_c:504:0.00000000515:614:118:109
  • Raw architecture: dCache_1:193:0.000000989:300:112:195#HAMP:319:0.000000000106:389:71:69#His_kinase:405:1.94e-30:484:80:80#HATPase_c:504:0.00000000515:614:118:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000371445::NZ_KB850951.1::G00096
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1665587-1668947Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1093_03818RefSeq proteinWP_002603582.1
Context group IDGCF_000371445::NZ_KB850951.1::G00096
Context members
HMPREF1093_RS18965HMPREF1093_RS18970
Partner locus tags
HMPREF1093_RS18965HMPREF1093_RS18970
Partner old locus tags
HMPREF1093_03818HMPREF1093_03819
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_002603582.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1093_RS18965Primary locus identifier stored in the genes table.
Old locus tagHMPREF1093_03818Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB850951.1Sequence record reported by the local genomic context database.
Genomic interval1 665 587-1 667 476 nt1 890 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 665 587-1 668 947 ntGCF_000371445::NZ_KB850951.1::G00096

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000371445::NZ_KB850951.1::G00096

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB850951.1All displayed genes belong to this local TCS context.
Neighborhood span1 665 587-1 668 947 nt3 361 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 665 587 nt1 668 947 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF1093_RS18965GCF_000371445#HMPREF1093_RS18965
HKClassicCurrent focus

1 665 587-1 667 476 nt · Forward (+)

Old locus HMPREF1093_03818RefSeq WP_002603582.1
HMPREF1093_RS18970GCF_000371445#HMPREF1093_RS18970
RRunclassified

1 667 451-1 668 947 nt · Forward (+)

Old locus HMPREF1093_03819RefSeq WP_002603583.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0950770Run 6 · HK · 6 sequences
Representative sequenceGCF_000371445#HMPREF1093_RS18965The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0950770

Simplified PFAM architecture for HKOC_0950770

PFAM domain coverage: 242 / 629 aa (38.5%)

1 aa629 aa
HAMP: 339-389 aaHAMPHis_kinase: 406-484 aaHis_kinaseHATPase_c: 503-614 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[339-389] | His_kinase[406-484] | HATPase_c[503-614]
  • Domain count: 3
  • Matched identifier: HKOC_0950770
  • Positioned domains: HAMP 339-389 ; His_kinase 406-484 ; HATPase_c 503-614
Cluster members and taxonomy
Visualization

Representative gene: GCF_000371445#HMPREF1093_RS18965

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 999 412 · GCF_000371445
AssemblyClos_hath_12489931_V1 · Scaffoldhaploid
Genome composition6 873 024 bp · 49,5% GCHungatella hathewayi 12489931
Signal transduction countsGenes 266 · HK 130 · RR 132CheA 1 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusHungatella
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Hungatella

Related genes

Preview from the same derived genome key