Gene detail

HMPREF1093_RS00265

Histidine kinase, Classic

Hungatella hathewayi 12489931 · GCF_000371445

ClassHKTypeClassicLength580 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000371445#HMPREF1093_RS00265Stable P2CS identifier used across views.
GenomeGCF_000371445Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella
Selected clusterHKOC_1161930Run 6 · 7 sequences · id 100% · cov 80% · representative
External referencesWP_002599866.1 · A0A6N3I6W4 · MIST4 HMPREF1093_RS00265RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length580 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage205 / 580 aa (35.3%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa580 aa
HAMP: 290-360 aa (71 aa)1His_kinase: 376-454 aa (79 aa)2HATPase_c: 472-526 aa (55 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
290-360 aa · 71 aa · 12.2% of protein
Raw tokenHAMP:290:0.0000000000135:360:71:69
2 His_kinase#2
376-454 aa · 79 aa · 13.6% of protein
Raw tokenHis_kinase:376:1.16e-24:454:80:80
3 HATPase_c#3
472-526 aa · 55 aa · 9.5% of protein
Raw tokenHATPase_c:472:0.00000199:526:55:109
  • Raw architecture: HAMP:290:0.0000000000135:360:71:69#His_kinase:376:1.16e-24:454:80:80#HATPase_c:472:0.00000199:526:55:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000371445::NZ_KB850950.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span55547-58988Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1093_00052RefSeq proteinWP_002599866.1
Context group IDGCF_000371445::NZ_KB850950.1::G00002
Context members
HMPREF1093_RS00260HMPREF1093_RS00265
Partner locus tags
HMPREF1093_RS00260HMPREF1093_RS00265
Partner old locus tags
HMPREF1093_00051HMPREF1093_00052
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002599866.1Primary protein accession used for annex mappings.
UniProt accessionA0A6N3I6W4Primary UniProt accession resolved in the annex database.
UniProt IDA0A6N3I6W4_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1093_RS00265Primary locus identifier stored in the genes table.
Old locus tagHMPREF1093_00052Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB850950.1Sequence record reported by the local genomic context database.
Genomic interval57 246-58 988 nt1 743 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span55 547-58 988 ntGCF_000371445::NZ_KB850950.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000371445::NZ_KB850950.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB850950.1All displayed genes belong to this local TCS context.
Neighborhood span55 547-58 988 nt3 442 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
55 547 nt58 988 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF1093_RS00260GCF_000371445#HMPREF1093_RS00260
RRunclassified

55 547-57 244 nt · Reverse (-)

Old locus HMPREF1093_00051RefSeq WP_002599865.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1161930Run 6 · HK · 7 sequences
Representative sequenceGCF_000371445#HMPREF1093_RS00265The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1161930

Simplified PFAM architecture for HKOC_1161930

PFAM domain coverage: 132 / 580 aa (22.8%)

1 aa580 aa
HAMP: 307-360 aaHAMPHis_kinase: 376-453 aaHis_kinase
HAMPHis_kinase
  • Simplified architecture: HAMP + His_kinase
  • Raw architecture: HAMP[307-360] | His_kinase[376-453]
  • Domain count: 2
  • Matched identifier: HKOC_1161930
  • Positioned domains: HAMP 307-360 ; His_kinase 376-453
Cluster members and taxonomy
Visualization

Representative gene: GCF_000371445#HMPREF1093_RS00265

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 999 412 · GCF_000371445
AssemblyClos_hath_12489931_V1 · Scaffoldhaploid
Genome composition6 873 024 bp · 49,5% GCHungatella hathewayi 12489931
Signal transduction countsGenes 266 · HK 130 · RR 132CheA 1 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusHungatella
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Hungatella

Related genes

Preview from the same derived genome key