Gene detail

HMPREF1093_RS12480

Histidine kinase, Classic

Hungatella hathewayi 12489931 · GCF_000371445

ClassHKTypeClassicLength605 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000371445#HMPREF1093_RS12480Stable P2CS identifier used across views.
GenomeGCF_000371445Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella
Selected clusterHKOC_1028509Run 6 · 5 sequences · id 100% · cov 80% · representative
External referencesWP_002602288.1 · A0A3E3DE13 · MIST4 HMPREF1093_RS12480RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length605 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage375 / 605 aa (62.0%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa605 aa
dCache_1: 173-284 aa (112 aa)1HAMP: 301-375 aa (75 aa)2His_kinase: 391-470 aa (80 aa)3HATPase_c: 487-594 aa (108 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
173-284 aa · 112 aa · 18.5% of protein
Raw tokendCache_1:173:0.0000304:284:116:195
2 HAMP#2
301-375 aa · 75 aa · 12.4% of protein
Raw tokenHAMP:301:0.0000000222:375:76:69
3 His_kinase#3
391-470 aa · 80 aa · 13.2% of protein
Raw tokenHis_kinase:391:2.06e-27:470:80:80
4 HATPase_c#4
487-594 aa · 108 aa · 17.9% of protein
Raw tokenHATPase_c:487:0.000000313:594:109:109
  • Raw architecture: dCache_1:173:0.0000304:284:116:195#HAMP:301:0.0000000222:375:76:69#His_kinase:391:2.06e-27:470:80:80#HATPase_c:487:0.000000313:594:109:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000371445::NZ_KB850951.1::G00074
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span245673-248363Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1093_02506RefSeq proteinWP_002602288.1
Context group IDGCF_000371445::NZ_KB850951.1::G00074
Context members
HMPREF1093_RS12475HMPREF1093_RS12480
Partner locus tags
HMPREF1093_RS12475HMPREF1093_RS12480
Partner old locus tags
HMPREF1093_02505HMPREF1093_02506
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002602288.1Primary protein accession used for annex mappings.
UniProt accessionA0A3E3DE13Primary UniProt accession resolved in the annex database.
UniProt IDA0A3E3DE13_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1093_RS12480Primary locus identifier stored in the genes table.
Old locus tagHMPREF1093_02506Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB850951.1Sequence record reported by the local genomic context database.
Genomic interval246 546-248 363 nt1 818 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span245 673-248 363 ntGCF_000371445::NZ_KB850951.1::G00074

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000371445::NZ_KB850951.1::G00074

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB850951.1All displayed genes belong to this local TCS context.
Neighborhood span245 673-248 363 nt2 691 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
245 673 nt248 363 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF1093_RS12475GCF_000371445#HMPREF1093_RS12475
RRunclassified

245 673-246 428 nt · Reverse (-)

Old locus HMPREF1093_02505RefSeq WP_002602287.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1028509Run 6 · HK · 5 sequences
Representative sequenceGCF_000371445#HMPREF1093_RS12480The current gene is the representative for this cluster.
PFAM architectureHis_kinase1 domain in the representative PFAM annotation.

PFAM architecture for HKOC_1028509

Simplified PFAM architecture for HKOC_1028509

PFAM domain coverage: 79 / 605 aa (13.1%)

1 aa605 aa
His_kinase: 391-469 aaHis_kinase
His_kinase
  • Simplified architecture: His_kinase
  • Raw architecture: His_kinase[391-469]
  • Domain count: 1
  • Matched identifier: HKOC_1028509
  • Positioned domains: His_kinase 391-469
Cluster members and taxonomy
Visualization

Representative gene: GCF_000371445#HMPREF1093_RS12480

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 999 412 · GCF_000371445
AssemblyClos_hath_12489931_V1 · Scaffoldhaploid
Genome composition6 873 024 bp · 49,5% GCHungatella hathewayi 12489931
Signal transduction countsGenes 266 · HK 130 · RR 132CheA 1 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusHungatella
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Hungatella

Related genes

Preview from the same derived genome key