Gene detail

HMPREF1093_RS12370

Histidine kinase, Classic

Hungatella hathewayi 12489931 · GCF_000371445

ClassHKTypeClassicLength588 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000371445#HMPREF1093_RS12370Stable P2CS identifier used across views.
GenomeGCF_000371445Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella
Selected clusterHKOC_1120116Run 6 · 12 sequences · id 100% · cov 80% · representative
External referencesWP_002602268.1 · A0A3E4TZZ1 · MIST4 HMPREF1093_RS12370RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length588 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage493 / 588 aa (83.8%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa588 aa
dCache_1: 32-265 aa (234 aa)1HAMP: 282-351 aa (70 aa)2His_kinase: 373-452 aa (80 aa)3HATPase_c: 471-579 aa (109 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
32-265 aa · 234 aa · 39.8% of protein
Raw tokendCache_1:32:0.000000959:265:241:195
2 HAMP#2
282-351 aa · 70 aa · 11.9% of protein
Raw tokenHAMP:282:0.0000000000000172:351:70:69
3 His_kinase#3
373-452 aa · 80 aa · 13.6% of protein
Raw tokenHis_kinase:373:2.08e-26:452:80:80
4 HATPase_c#4
471-579 aa · 109 aa · 18.5% of protein
Raw tokenHATPase_c:471:0.000000000242:579:111:109
  • Raw architecture: dCache_1:32:0.000000959:265:241:195#HAMP:282:0.0000000000000172:351:70:69#His_kinase:373:2.08e-26:452:80:80#HATPase_c:471:0.000000000242:579:111:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000371445::NZ_KB850951.1::G00073
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span224200-226796Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1093_02485RefSeq proteinWP_002602268.1
Context group IDGCF_000371445::NZ_KB850951.1::G00073
Context members
HMPREF1093_RS12370HMPREF1093_RS12375
Partner locus tags
HMPREF1093_RS12370HMPREF1093_RS12375
Partner old locus tags
HMPREF1093_02485HMPREF1093_02486
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002602268.1Primary protein accession used for annex mappings.
UniProt accessionA0A3E4TZZ1Primary UniProt accession resolved in the annex database.
UniProt IDA0A3E4TZZ1_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1093_RS12370Primary locus identifier stored in the genes table.
Old locus tagHMPREF1093_02485Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB850951.1Sequence record reported by the local genomic context database.
Genomic interval224 200-225 966 nt1 767 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span224 200-226 796 ntGCF_000371445::NZ_KB850951.1::G00073

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000371445::NZ_KB850951.1::G00073

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB850951.1All displayed genes belong to this local TCS context.
Neighborhood span224 200-226 796 nt2 597 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
224 200 nt226 796 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF1093_RS12375GCF_000371445#HMPREF1093_RS12375
RRunclassified

225 963-226 796 nt · Forward (+)

Old locus HMPREF1093_02486RefSeq WP_002602269.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1120116Run 6 · HK · 12 sequences
Representative sequenceGCF_000371445#HMPREF1093_RS12370The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1120116

Simplified PFAM architecture for HKOC_1120116

PFAM domain coverage: 242 / 588 aa (41.2%)

1 aa588 aa
HAMP: 300-351 aaHAMPHis_kinase: 373-452 aaHis_kinaseHATPase_c: 471-580 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[300-351] | His_kinase[373-452] | HATPase_c[471-580]
  • Domain count: 3
  • Matched identifier: HKOC_1120116
  • Positioned domains: HAMP 300-351 ; His_kinase 373-452 ; HATPase_c 471-580
Cluster members and taxonomy
Visualization

Representative gene: GCF_000371445#HMPREF1093_RS12370

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 999 412 · GCF_000371445
AssemblyClos_hath_12489931_V1 · Scaffoldhaploid
Genome composition6 873 024 bp · 49,5% GCHungatella hathewayi 12489931
Signal transduction countsGenes 266 · HK 130 · RR 132CheA 1 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusHungatella
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Hungatella

Related genes

Preview from the same derived genome key