Gene detail

HMPREF1093_RS07170

Histidine kinase, Classic

Hungatella hathewayi 12489931 · GCF_000371445

ClassHKTypeClassicLength603 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000371445#HMPREF1093_RS07170Stable P2CS identifier used across views.
GenomeGCF_000371445Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella
Selected clusterHKOC_1037140Run 6 · 8 sequences · id 100% · cov 80% · representative
External referencesWP_002601251.1 · A0A3E3DS10 · MIST4 HMPREF1093_RS07170RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length603 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage510 / 603 aa (84.6%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa603 aa
dCache_1: 41-291 aa (251 aa)1HAMP: 310-379 aa (70 aa)2His_kinase: 396-475 aa (80 aa)3HATPase_c: 492-600 aa (109 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
41-291 aa · 251 aa · 41.6% of protein
Raw tokendCache_1:41:0.0000000000952:291:251:195
2 HAMP#2
310-379 aa · 70 aa · 11.6% of protein
Raw tokenHAMP:310:0.000000000000292:379:70:69
3 His_kinase#3
396-475 aa · 80 aa · 13.3% of protein
Raw tokenHis_kinase:396:5.72e-30:475:80:80
4 HATPase_c#4
492-600 aa · 109 aa · 18.1% of protein
Raw tokenHATPase_c:492:0.0000000471:600:112:109
  • Raw architecture: dCache_1:41:0.0000000000952:291:251:195#HAMP:310:0.000000000000292:379:70:69#His_kinase:396:5.72e-30:475:80:80#HATPase_c:492:0.0000000471:600:112:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000371445::NZ_KB850950.1::G00041
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1669230-1672576Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1093_01443RefSeq proteinWP_002601251.1
Context group IDGCF_000371445::NZ_KB850950.1::G00041
Context members
HMPREF1093_RS07170HMPREF1093_RS07175
Partner locus tags
HMPREF1093_RS07170HMPREF1093_RS07175
Partner old locus tags
HMPREF1093_01443HMPREF1093_01444
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002601251.1Primary protein accession used for annex mappings.
UniProt accessionA0A3E3DS10Primary UniProt accession resolved in the annex database.
UniProt IDA0A3E3DS10_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1093_RS07170Primary locus identifier stored in the genes table.
Old locus tagHMPREF1093_01443Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB850950.1Sequence record reported by the local genomic context database.
Genomic interval1 669 230-1 671 041 nt1 812 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 669 230-1 672 576 ntGCF_000371445::NZ_KB850950.1::G00041

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000371445::NZ_KB850950.1::G00041

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB850950.1All displayed genes belong to this local TCS context.
Neighborhood span1 669 230-1 672 576 nt3 347 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 669 230 nt1 672 576 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF1093_RS07170GCF_000371445#HMPREF1093_RS07170
HKClassicCurrent focus

1 669 230-1 671 041 nt · Forward (+)

Old locus HMPREF1093_01443RefSeq WP_002601251.1
HMPREF1093_RS07175GCF_000371445#HMPREF1093_RS07175
RRunclassified

1 671 038-1 672 576 nt · Forward (+)

Old locus HMPREF1093_01444RefSeq WP_002601252.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1037140Run 6 · HK · 8 sequences
Representative sequenceGCF_000371445#HMPREF1093_RS07170The current gene is the representative for this cluster.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1037140

Simplified PFAM architecture for HKOC_1037140

PFAM domain coverage: 474 / 603 aa (78.6%)

1 aa603 aa
dCache_1: 43-279 aadCache_1HAMP: 327-379 aaHAMPHis_kinase: 396-473 aaHis_kinaseHATPase_c: 494-599 aaHATPase_c
dCache_1HAMPHis_kinaseHATPase_c
  • Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
  • Raw architecture: dCache_1[43-279] | HAMP[327-379] | His_kinase[396-473] | HATPase_c[494-599]
  • Domain count: 4
  • Matched identifier: HKOC_1037140
  • Positioned domains: dCache_1 43-279 ; HAMP 327-379 ; His_kinase 396-473 ; HATPase_c 494-599
Cluster members and taxonomy
Visualization

Representative gene: GCF_000371445#HMPREF1093_RS07170

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 999 412 · GCF_000371445
AssemblyClos_hath_12489931_V1 · Scaffoldhaploid
Genome composition6 873 024 bp · 49,5% GCHungatella hathewayi 12489931
Signal transduction countsGenes 266 · HK 130 · RR 132CheA 1 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusHungatella
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Hungatella

Related genes

Preview from the same derived genome key