Gene detail

HMPREF1093_RS04650

Histidine kinase, Classic

Hungatella hathewayi 12489931 · GCF_000371445

ClassHKTypeClassicLength602 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000371445#HMPREF1093_RS04650Stable P2CS identifier used across views.
GenomeGCF_000371445Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella
Selected clusterHKOC_1042036Run 6 · 13 sequences · id 100% · cov 80% · representative
External referencesWP_002600748.1 · A0A374NY76 · MIST4 HMPREF1093_RS04650RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length602 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage401 / 602 aa (66.6%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa602 aa
dCache_1: 122-260 aa (139 aa)1HAMP: 297-365 aa (69 aa)2His_kinase: 380-459 aa (80 aa)3HATPase_c: 478-590 aa (113 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
122-260 aa · 139 aa · 23.1% of protein
Raw tokendCache_1:122:0.000000245:260:142:195
2 HAMP#2
297-365 aa · 69 aa · 11.5% of protein
Raw tokenHAMP:297:0.0000000000000511:365:69:69
3 His_kinase#3
380-459 aa · 80 aa · 13.3% of protein
Raw tokenHis_kinase:380:7.44e-30:459:80:80
4 HATPase_c#4
478-590 aa · 113 aa · 18.8% of protein
Raw tokenHATPase_c:478:0.00000000000218:590:114:109
  • Raw architecture: dCache_1:122:0.000000245:260:142:195#HAMP:297:0.0000000000000511:365:69:69#His_kinase:380:7.44e-30:459:80:80#HATPase_c:478:0.00000000000218:590:114:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000371445::NZ_KB850950.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1074359-1077701Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1093_00937RefSeq proteinWP_002600748.1
Context group IDGCF_000371445::NZ_KB850950.1::G00030
Context members
HMPREF1093_RS04645HMPREF1093_RS04650
Partner locus tags
HMPREF1093_RS04645HMPREF1093_RS04650
Partner old locus tags
HMPREF1093_00936HMPREF1093_00937
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002600748.1Primary protein accession used for annex mappings.
UniProt accessionA0A374NY76Primary UniProt accession resolved in the annex database.
UniProt IDA0A374NY76_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1093_RS04650Primary locus identifier stored in the genes table.
Old locus tagHMPREF1093_00937Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB850950.1Sequence record reported by the local genomic context database.
Genomic interval1 075 893-1 077 701 nt1 809 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 074 359-1 077 701 ntGCF_000371445::NZ_KB850950.1::G00030

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000371445::NZ_KB850950.1::G00030

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB850950.1All displayed genes belong to this local TCS context.
Neighborhood span1 074 359-1 077 701 nt3 343 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 074 359 nt1 077 701 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF1093_RS04645GCF_000371445#HMPREF1093_RS04645
RRunclassified

1 074 359-1 075 915 nt · Reverse (-)

Old locus HMPREF1093_00936RefSeq WP_002600747.1
HMPREF1093_RS04650GCF_000371445#HMPREF1093_RS04650
HKClassicCurrent focus

1 075 893-1 077 701 nt · Reverse (-)

Old locus HMPREF1093_00937RefSeq WP_002600748.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1042036Run 6 · HK · 13 sequences
Representative sequenceGCF_000371445#HMPREF1093_RS04650The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1042036

Simplified PFAM architecture for HKOC_1042036

PFAM domain coverage: 243 / 602 aa (40.4%)

1 aa602 aa
HAMP: 313-364 aaHAMPHis_kinase: 381-458 aaHis_kinaseHATPase_c: 478-590 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[313-364] | His_kinase[381-458] | HATPase_c[478-590]
  • Domain count: 3
  • Matched identifier: HKOC_1042036
  • Positioned domains: HAMP 313-364 ; His_kinase 381-458 ; HATPase_c 478-590
Cluster members and taxonomy
Visualization

Representative gene: GCF_000371445#HMPREF1093_RS04650

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 999 412 · GCF_000371445
AssemblyClos_hath_12489931_V1 · Scaffoldhaploid
Genome composition6 873 024 bp · 49,5% GCHungatella hathewayi 12489931
Signal transduction countsGenes 266 · HK 130 · RR 132CheA 1 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusHungatella
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Hungatella

Related genes

Preview from the same derived genome key