1 HAMP#1
287-357 aa · 71 aa · 12.4% of protein
Raw token
HAMP:287:0.00000064:357:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1347_RS15575
Histidine kinase, Classic
Enterococcus faecium 504 · GCF_000295275
ClassHKTypeClassicLength574 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000295275#HMPREF1347_RS15575Stable P2CS identifier used across views.
GenomeGCF_000295275Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length574 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage255 / 574 aa (44.4%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa574 aa
Domain-by-domain annotation3 items
2 His_kinase#2
372-450 aa · 79 aa · 13.8% of protein
Raw token
His_kinase:372:2.41e-28:450:80:803 HATPase_c#3
469-573 aa · 105 aa · 18.3% of protein
Raw token
HATPase_c:469:0.000000000438:573:108:109- Raw architecture: HAMP:287:0.00000064:357:71:69#His_kinase:372:2.41e-28:450:80:80#HATPase_c:469:0.000000000438:573:108:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000295275::NZ_JH811570.1::G00019
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4502-7674Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1347_02671RefSeq proteinWP_002339906.1
Context group ID
GCF_000295275::NZ_JH811570.1::G00019Context members
HMPREF1347_RS15575HMPREF1347_RS15580
Partner locus tags
HMPREF1347_RS15575HMPREF1347_RS15580
Partner old locus tags
HMPREF1347_02671HMPREF1347_02672
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_002339906.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1347_RS15575Primary locus identifier stored in the genes table.
Old locus tagHMPREF1347_02671Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH811570.1Sequence record reported by the local genomic context database.
Genomic interval4 502-6 226 nt1 725 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 502-7 674 ntGCF_000295275::NZ_JH811570.1::G00019
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000295275::NZ_JH811570.1::G00019Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH811570.1All displayed genes belong to this local TCS context.
Neighborhood span4 502-7 674 nt3 173 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 502 nt7 674 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1347_RS15575GCF_000295275#HMPREF1347_RS15575
HKClassicCurrent focus
4 502-6 226 nt · Forward (+)
HMPREF1347_RS15580GCF_000295275#HMPREF1347_RS15580
RRunclassified
6 223-7 674 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000295275#HMPREF1347_RS15575The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1192953
Simplified PFAM architecture for HKOC_1192953
PFAM domain coverage: 224 / 574 aa (39.0%)
1 aa574 aa
HAMPHis_kinaseHATPase_c
- Simplified architecture: HAMP + His_kinase + HATPase_c
- Raw architecture: HAMP[316-357] | His_kinase[372-449] | HATPase_c[469-572]
- Domain count: 3
- Matched identifier: HKOC_1192953
- Positioned domains: HAMP 316-357 ; His_kinase 372-449 ; HATPase_c 469-572
Cluster members and taxonomy
Representative gene: GCF_000295275#HMPREF1347_RS15575
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 134 805 · GCF_000295275
AssemblyASM29527v2 · Scaffoldhaploid
Genome composition2 617 730 bp · 38,0% GCEnterococcus faecium 504
Signal transduction countsGenes 35 · HK 18 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key