1 HAMP#1
201-253 aa · 53 aa · 11.0% of protein
Raw token
HAMP:201:0.0000123:253:53:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1347_RS03835
Histidine kinase, Classic
Enterococcus faecium 504 · GCF_000295275
ClassHKTypeClassicLength483 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000295275#HMPREF1347_RS03835Stable P2CS identifier used across views.
GenomeGCF_000295275Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length483 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 483 aa (50.7%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa483 aa
Domain-by-domain annotation3 items
2 His_kinase#2
268-347 aa · 80 aa · 16.6% of protein
Raw token
His_kinase:268:1.71e-27:347:80:803 HATPase_c#3
363-474 aa · 112 aa · 23.2% of protein
Raw token
HATPase_c:363:2.97e-16:474:113:109- Raw architecture: HAMP:201:0.0000123:253:53:69#His_kinase:268:1.71e-27:347:80:80#HATPase_c:363:2.97e-16:474:113:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000295275::NZ_JH811474.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span46595-49604Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1347_00048RefSeq proteinWP_002375385.1
Context group ID
GCF_000295275::NZ_JH811474.1::G00001Context members
HMPREF1347_RS03835HMPREF1347_RS03840
Partner locus tags
HMPREF1347_RS03835HMPREF1347_RS03840
Partner old locus tags
HMPREF1347_00048HMPREF1347_00049
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_002375385.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1347_RS03835Primary locus identifier stored in the genes table.
Old locus tagHMPREF1347_00048Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH811474.1Sequence record reported by the local genomic context database.
Genomic interval46 595-48 046 nt1 452 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span46 595-49 604 ntGCF_000295275::NZ_JH811474.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000295275::NZ_JH811474.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH811474.1All displayed genes belong to this local TCS context.
Neighborhood span46 595-49 604 nt3 010 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
46 595 nt49 604 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1347_RS03835GCF_000295275#HMPREF1347_RS03835
HKClassicCurrent focus
46 595-48 046 nt · Forward (+)
HMPREF1347_RS03840GCF_000295275#HMPREF1347_RS03840
RRunclassified
48 039-49 604 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000295275#HMPREF1347_RS03835The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1594231
Simplified PFAM architecture for HKOC_1594231
PFAM domain coverage: 239 / 483 aa (49.5%)
1 aa483 aa
HAMPHis_kinaseHATPase_c
- Simplified architecture: HAMP + His_kinase + HATPase_c
- Raw architecture: HAMP[204-253] | His_kinase[269-346] | HATPase_c[363-473]
- Domain count: 3
- Matched identifier: HKOC_1594231
- Positioned domains: HAMP 204-253 ; His_kinase 269-346 ; HATPase_c 363-473
Cluster members and taxonomy
Representative gene: GCF_000295275#HMPREF1347_RS03835
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 134 805 · GCF_000295275
AssemblyASM29527v2 · Scaffoldhaploid
Genome composition2 617 730 bp · 38,0% GCEnterococcus faecium 504
Signal transduction countsGenes 35 · HK 18 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key