1 HisKA_3#1
155-224 aa · 70 aa · 19.7% of protein
Raw token
HisKA_3:155:7.29e-21:224:70:68P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFME4453_RS00835
Histidine kinase, Classic
Enterococcus faecium E4453 · GCF_000239095
ClassHKTypeClassicLength355 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000239095#EFME4453_RS00835Stable P2CS identifier used across views.
GenomeGCF_000239095Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HisKA_3HATPase_c
Protein length355 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage160 / 355 aa (45.1%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa355 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
262-351 aa · 90 aa · 25.4% of protein
Raw token
HATPase_c:262:1.18e-18:351:105:109- Raw architecture: HisKA_3:155:7.29e-21:224:70:68#HATPase_c:262:1.18e-18:351:105:109
- Domain description: 1 HisKA_3,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000239095::NZ_AEDZ01000025.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span5768-7474Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEfmE4453_0271RefSeq proteinWP_002318624.1
Context group ID
GCF_000239095::NZ_AEDZ01000025.1::G00018Context members
EFME4453_RS00830EFME4453_RS00835
Partner locus tags
EFME4453_RS00830EFME4453_RS00835
Partner old locus tags
EfmE4453_0270EfmE4453_0271
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002318624.1Primary protein accession used for annex mappings.
UniProt accessionA0A829FA85Primary UniProt accession resolved in the annex database.
UniProt IDA0A829FA85_ENTFCDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFME4453_RS00835Primary locus identifier stored in the genes table.
Old locus tagEfmE4453_0271Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AEDZ01000025.1Sequence record reported by the local genomic context database.
Genomic interval6 407-7 474 nt1 068 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span5 768-7 474 ntGCF_000239095::NZ_AEDZ01000025.1::G00018
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000239095::NZ_AEDZ01000025.1::G00018Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AEDZ01000025.1All displayed genes belong to this local TCS context.
Neighborhood span5 768-7 474 nt1 707 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 768 nt7 474 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EFME4453_RS00830GCF_000239095#EFME4453_RS00830
RRNarL
5 768-6 400 nt · Reverse (-)
EFME4453_RS00835GCF_000239095#EFME4453_RS00835
HKClassicCurrent focus
6 407-7 474 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000172655#EFME1071_RS13385Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2775063
Simplified PFAM architecture for HKOC_2775063
PFAM domain coverage: 159 / 355 aa (44.8%)
1 aa355 aa
HisKA_3HATPase_c
- Simplified architecture: HisKA_3 + HATPase_c
- Raw architecture: HisKA_3[155-223] | HATPase_c[262-351]
- Domain count: 2
- Matched identifier: HKOC_2775063
- Positioned domains: HisKA_3 155-223 ; HATPase_c 262-351
Cluster members and taxonomy
Representative gene: GCF_000172655#EFME1071_RS13385
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 873 127 · GCF_000239095
AssemblyASM23909v2 · Contighaploid
Genome composition2 819 308 bp · 38,0% GCEnterococcus faecium E4453
Signal transduction countsGenes 36 · HK 17 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key