1 HAMP#1
198-268 aa · 71 aa · 14.2% of protein
Raw token
HAMP:198:0.000000000000542:268:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFME4453_RS01825
Histidine kinase, Classic
Enterococcus faecium E4453 · GCF_000239095
ClassHKTypeClassicLength501 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000239095#EFME4453_RS01825Stable P2CS identifier used across views.
GenomeGCF_000239095Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length501 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage249 / 501 aa (49.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa501 aa
Domain-by-domain annotation3 items
2 HisKA#2
273-339 aa · 67 aa · 13.4% of protein
Raw token
HisKA:273:0.00000000000000327:339:67:643 HATPase_c#3
387-497 aa · 111 aa · 22.2% of protein
Raw token
HATPase_c:387:8.61e-28:497:111:109- Raw architecture: HAMP:198:0.000000000000542:268:71:69#HisKA:273:0.00000000000000327:339:67:64#HATPase_c:387:8.61e-28:497:111:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000239095::NZ_AEDZ01000048.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3722-5910Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEfmE4453_2742RefSeq proteinWP_002298265.1
Context group ID
GCF_000239095::NZ_AEDZ01000048.1::G00016Context members
EFME4453_RS01820EFME4453_RS01825
Partner locus tags
EFME4453_RS01820EFME4453_RS01825
Partner old locus tags
EfmE4453_2741EfmE4453_2742
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002298265.1Primary protein accession used for annex mappings.
UniProt accessionQ3XYQ7Primary UniProt accession resolved in the annex database.
UniProt IDQ3XYQ7_ENTFDDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFME4453_RS01825Primary locus identifier stored in the genes table.
Old locus tagEfmE4453_2742Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AEDZ01000048.1Sequence record reported by the local genomic context database.
Genomic interval4 405-5 910 nt1 506 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span3 722-5 910 ntGCF_000239095::NZ_AEDZ01000048.1::G00016
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000239095::NZ_AEDZ01000048.1::G00016Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AEDZ01000048.1All displayed genes belong to this local TCS context.
Neighborhood span3 722-5 910 nt2 189 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 722 nt5 910 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EFME4453_RS01820GCF_000239095#EFME4453_RS01820
RROmpR
3 722-4 408 nt · Forward (+)
EFME4453_RS01825GCF_000239095#EFME4453_RS01825
HKClassicCurrent focus
4 405-5 910 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_011316265#BXA52_RS13740Use this link to inspect the representative gene detail.
PFAM architectureArlS_N + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1416543
Simplified PFAM architecture for HKOC_1416543
PFAM domain coverage: 377 / 513 aa (73.5%)
1 aa513 aa
ArlS_NHAMPHisKAHATPase_c
- Simplified architecture: ArlS_N + HAMP + HisKA + HATPase_c
- Raw architecture: ArlS_N[46-193] | HAMP[215-268] | HisKA[274-339] | HATPase_c[388-496]
- Domain count: 4
- Matched identifier: HKOC_1416543
- Positioned domains: ArlS_N 46-193 ; HAMP 215-268 ; HisKA 274-339 ; HATPase_c 388-496
Cluster members and taxonomy
Representative gene: GCF_011316265#BXA52_RS13740
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 873 127 · GCF_000239095
AssemblyASM23909v2 · Contighaploid
Genome composition2 819 308 bp · 38,0% GCEnterococcus faecium E4453
Signal transduction countsGenes 36 · HK 17 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key