1 HisKA_3#1
172-235 aa · 64 aa · 17.8% of protein
Raw token
HisKA_3:172:5.94e-16:235:66:68P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFME4453_RS05540
Histidine kinase, Classic
Enterococcus faecium E4453 · GCF_000239095
ClassHKTypeClassicLength359 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000239095#EFME4453_RS05540Stable P2CS identifier used across views.
GenomeGCF_000239095Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HisKA_3HATPase_c
Protein length359 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage146 / 359 aa (40.7%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa359 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
275-356 aa · 82 aa · 22.8% of protein
Raw token
HATPase_c:275:0.000000242:356:100:109- Raw architecture: HisKA_3:172:5.94e-16:235:66:68#HATPase_c:275:0.000000242:356:100:109
- Domain description: 1 HisKA_3,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000239095::NZ_AEDZ01000158.1::G00015
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span15975-17710Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEfmE4453_0491RefSeq proteinWP_002317394.1
Context group ID
GCF_000239095::NZ_AEDZ01000158.1::G00015Context members
EFME4453_RS05540EFME4453_RS05545
Partner locus tags
EFME4453_RS05540EFME4453_RS05545
Partner old locus tags
EfmE4453_0491EfmE4453_0492
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002317394.1Primary protein accession used for annex mappings.
UniProt accessionA0AAV3GYF7Primary UniProt accession resolved in the annex database.
UniProt IDA0AAV3GYF7_ENTFCDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFME4453_RS05540Primary locus identifier stored in the genes table.
Old locus tagEfmE4453_0491Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AEDZ01000158.1Sequence record reported by the local genomic context database.
Genomic interval15 975-17 084 nt1 110 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span15 975-17 710 ntGCF_000239095::NZ_AEDZ01000158.1::G00015
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000239095::NZ_AEDZ01000158.1::G00015Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AEDZ01000158.1All displayed genes belong to this local TCS context.
Neighborhood span15 975-17 710 nt1 736 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
15 975 nt17 710 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EFME4453_RS05540GCF_000239095#EFME4453_RS05540
HKClassicCurrent focus
15 975-17 084 nt · Forward (+)
EFME4453_RS05545GCF_000239095#EFME4453_RS05545
RRNarL
17 081-17 710 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000172675#EFME1162_RS10350Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c_52 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2691252
Simplified PFAM architecture for HKOC_2691252
PFAM domain coverage: 150 / 369 aa (40.7%)
1 aa369 aa
HisKA_3HATPase_c_5
- Simplified architecture: HisKA_3 + HATPase_c_5
- Raw architecture: HisKA_3[182-245] | HATPase_c_5[279-364]
- Domain count: 2
- Matched identifier: HKOC_2691252
- Positioned domains: HisKA_3 182-245 ; HATPase_c_5 279-364
Cluster members and taxonomy
Representative gene: GCF_000172675#EFME1162_RS10350
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 873 127 · GCF_000239095
AssemblyASM23909v2 · Contighaploid
Genome composition2 819 308 bp · 38,0% GCEnterococcus faecium E4453
Signal transduction countsGenes 36 · HK 17 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key