1 Response_reg#1
6-113 aa · 108 aa · 19.5% of protein
Raw token
Response_reg:6:1.26e-23:113:109:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ROI_RS15605
Response regulator, PleD_VieA family
Roseburia intestinalis M50/1 · GCF_000209995
ClassRRTypePleD_VieALength554 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000209995#ROI_RS15605Stable P2CS identifier used across views.
GenomeGCF_000209995Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
Response_regGGDEFEAL
Protein length554 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage491 / 554 aa (88.6%)Merged over positioned domains only.
Domain description1 Response_reg,1 GGDEF,1 EALSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa554 aa
Domain-by-domain annotation3 items
2 GGDEF#2
133-278 aa · 146 aa · 26.4% of protein
Raw token
GGDEF:133:1.34e-19:278:154:1603 EAL#3
303-539 aa · 237 aa · 42.8% of protein
Raw token
EAL:303:2.91e-74:539:237:235- Raw architecture: Response_reg:6:1.26e-23:113:109:111#GGDEF:133:1.34e-19:278:154:160#EAL:303:2.91e-74:539:237:235
- Domain description: 1 Response_reg,1 GGDEF,1 EAL
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000209995::NC_021040.1::G00051
Group size11 locus tag listed below.
HK / RR0 / 1Counts resolved for the local TCS neighborhood.
Context span3371219-3372883Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROI_33760RefSeq proteinWP_015521781.1
Context group ID
GCF_000209995::NC_021040.1::G00051Context members
ROI_RS15605
Partner locus tags
ROI_RS15605
Partner old locus tags
ROI_33760
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_015521781.1Primary protein accession used for annex mappings.
UniProt accessionD4L1F8Primary UniProt accession resolved in the annex database.
UniProt IDD4L1F8_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagROI_RS15605Primary locus identifier stored in the genes table.
Old locus tagROI_33760Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_021040.1Sequence record reported by the local genomic context database.
Genomic interval3 371 219-3 372 883 nt1 665 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span3 371 219-3 372 883 ntGCF_000209995::NC_021040.1::G00051
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000209995::NC_021040.1::G00051Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_021040.1All displayed genes belong to this local TCS context.
Neighborhood span3 371 219-3 372 883 nt1 665 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 371 219 nt3 372 883 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
ROI_RS15605GCF_000209995#ROI_RS15605
RRPleD_VieACurrent focus
3 371 219-3 372 883 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000209995#ROI_RS15605The current gene is the representative for this cluster.
PFAM architectureResponse_reg + GGDEF + EAL3 domains in the representative PFAM annotation.
PFAM architecture for RROC_0067729
Simplified PFAM architecture for RROC_0067729
PFAM domain coverage: 492 / 554 aa (88.8%)
1 aa554 aa
Response_regGGDEFEAL
- Simplified architecture: Response_reg + GGDEF + EAL
- Raw architecture: Response_reg[6-113] | GGDEF[133-280] | EAL[304-539]
- Domain count: 3
- Matched identifier: RROC_0067729
- Positioned domains: Response_reg 6-113 ; Response_reg 6-113 ; GGDEF 133-280 ; GGDEF 133-280 ; EAL 304-539 ; EAL 304-539
Cluster members and taxonomy
Representative gene: GCF_000209995#ROI_RS15605
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 657 315 · GCF_000209995
AssemblyASM20999v1 · Chromosomehaploid
Genome composition4 143 550 bp · 42,5% GCRoseburia intestinalis M50/1
Signal transduction countsGenes 106 · HK 45 · RR 57CheA 1 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key