1 HAMP#1
174-244 aa · 71 aa · 15.2% of protein
Raw token
HAMP:174:0.000000000000368:244:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ROI_RS00135
Histidine kinase, Classic
Roseburia intestinalis M50/1 · GCF_000209995
ClassHKTypeClassicLength466 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000209995#ROI_RS00135Stable P2CS identifier used across views.
GenomeGCF_000209995Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length466 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 466 aa (52.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa466 aa
Domain-by-domain annotation3 items
2 HisKA#2
251-313 aa · 63 aa · 13.5% of protein
Raw token
HisKA:251:0.00000000000000477:313:63:643 HATPase_c#3
358-466 aa · 109 aa · 23.4% of protein
Raw token
HATPase_c:358:1.82e-31:466:109:109- Raw architecture: HAMP:174:0.000000000000368:244:71:69#HisKA:251:0.00000000000000477:313:63:64#HATPase_c:358:1.82e-31:466:109:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000209995::NC_021040.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span23223-25301Genomic interval covered by the local TCS group.
Identifiers
Old locus tagROI_00380RefSeq proteinWP_015520056.1
Context group ID
GCF_000209995::NC_021040.1::G00002Context members
ROI_RS00130ROI_RS00135
Partner locus tags
ROI_RS00130ROI_RS00135
Partner old locus tags
ROI_00370ROI_00380
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_015520056.1Primary protein accession used for annex mappings.
UniProt accessionD4KUT3Primary UniProt accession resolved in the annex database.
UniProt IDD4KUT3_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagROI_RS00135Primary locus identifier stored in the genes table.
Old locus tagROI_00380Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_021040.1Sequence record reported by the local genomic context database.
Genomic interval23 901-25 301 nt1 401 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span23 223-25 301 ntGCF_000209995::NC_021040.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000209995::NC_021040.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_021040.1All displayed genes belong to this local TCS context.
Neighborhood span23 223-25 301 nt2 079 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
23 223 nt25 301 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ROI_RS00130GCF_000209995#ROI_RS00130
RROmpR
23 223-23 897 nt · Forward (+)
ROI_RS00135GCF_000209995#ROI_RS00135
HKClassicCurrent focus
23 901-25 301 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000209995#ROI_RS00135The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1761840
Simplified PFAM architecture for HKOC_1761840
PFAM domain coverage: 225 / 466 aa (48.3%)
1 aa466 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[191-244] | HisKA[251-313] | HATPase_c[359-466]
- Domain count: 3
- Matched identifier: HKOC_1761840
- Positioned domains: HAMP 191-244 ; HisKA 251-313 ; HATPase_c 359-466
Cluster members and taxonomy
Representative gene: GCF_000209995#ROI_RS00135
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 657 315 · GCF_000209995
AssemblyASM20999v1 · Chromosomehaploid
Genome composition4 143 550 bp · 42,5% GCRoseburia intestinalis M50/1
Signal transduction countsGenes 106 · HK 45 · RR 57CheA 1 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia
Related genes
Preview from the same derived genome key