Gene detail

EC50959_RS07765

Histidine kinase, Unorthodox

Escherichia coli 5.0959 · GCF_000194395

Open genome Open selected cluster RefSeq UniProt

ClassHKTypeUnorthodoxLength1197 aaTM0ValidatedNoCompleteYesContextpaired

Gene IDGCF_000194395#EC50959_RS07765Stable P2CS identifier used across views.

GenomeGCF_000194395Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia

Selected clusterHKOC_0161067Run 6 · 146 sequences · id 100% · cov 80% · representative

External referencesWP_001399259.1 · A0AAP9MU13 · MIST4 EC50959_RS07765RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PBPbHisKAHATPase_cResponse_regHpt

Protein length1197 aaLength used to scale native and Biotite-like views.

Annotated domains66 with usable coordinates.

Domain coverage796 / 1197 aa (66.5%)Merged over positioned domains only.

Domain description2 PBPb,1 HisKA,1 HATPase_c,1 Response_reg,1 HptSummary string stored in the genes table.

Signal peptideUnavailableNo TMPRED prediction file matched this gene.

Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.

Complete domain annotations

Domain view

Native Biotite-like

Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.

1 aa1197 aa

Domain-by-domain annotation6 items

1 PBPb#1

73-276 aa · 204 aa · 17.0% of protein

Raw tokenPBPb:73:0.00000000000000521:276:209:219

2 PBPb#2

304-519 aa · 216 aa · 18.0% of protein

Raw tokenPBPb:304:7.37e-40:519:223:219

3 HisKA#3

711-777 aa · 67 aa · 5.6% of protein

Raw tokenHisKA:711:1.95e-16:777:67:64

4 HATPase_c#4

825-938 aa · 114 aa · 9.5% of protein

Raw tokenHATPase_c:825:3.88e-32:938:114:109

5 Response_reg#5

961-1070 aa · 110 aa · 9.2% of protein

Raw tokenResponse_reg:961:1.51e-39:1070:110:111

6 Hpt#6

1104-1188 aa · 85 aa · 7.1% of protein

Raw tokenHpt:1104:0.0000000898:1188:85:84

Raw architecture: PBPb:73:0.00000000000000521:276:209:219#PBPb:304:7.37e-40:519:223:219#HisKA:711:1.95e-16:777:67:64#HATPase_c:825:3.88e-32:938:114:109#Response_reg:961:1.51e-39:1070:110:111#Hpt:1104:0.0000000898:1188:85:84
Domain description: 2 PBPb,1 HisKA,1 HATPase_c,1 Response_reg,1 Hpt
TM description: N/A
TMPRED source: No TMPRED file loaded
TMPRED segments: N/A
Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000194395::NZ_AEZX02000014.1::G00008

Group size22 locus tags listed below.

HK / RR1 / 1Counts resolved for the local TCS neighborhood.

Context span264747-268959Genomic interval covered by the local TCS group.

Identifiers

Old locus tagEC50959_3828RefSeq proteinWP_001399259.1

Context group IDGCF_000194395::NZ_AEZX02000014.1::G00008

Context members

EC50959_RS07765EC50959_RS07760

Partner locus tags

EC50959_RS07765EC50959_RS07760

Partner old locus tags

EC50959_3828EC50959_3829

Partner protein IDs

WP_001399259.1 WP_000991370.1

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001399259.1Primary protein accession used for annex mappings.

UniProt accessionA0AAP9MU13Primary UniProt accession resolved in the annex database.

UniProt IDA0AAP9MU13_ECOLXDisplay identifier provided by UniProt.

GO / PubMed4 / 0Unique GO terms and literature references available below.

Reference hubs

Open RefSeq Open UniProt accession

GO terms

GO:0005886 GO:0005524 GO:0009927 GO:0000155

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEC50959_RS07765Primary locus identifier stored in the genes table.

Old locus tagEC50959_3828Legacy locus tag recovered from the local context mapping.

Contig / repliconNZ_AEZX02000014.1Sequence record reported by the local genomic context database.

Genomic interval264 747-268 340 nt3 594 nt · Reverse (-)

StrandReverse (-)Strand sign follows the local context database convention.

Local TCS group span264 747-268 959 ntGCF_000194395::NZ_AEZX02000014.1::G00008

Quick actions

Open genome Search genes in genome

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000194395::NZ_AEZX02000014.1::G00008

Graphic view

Compact Biotite-like

Zoom

Full window Focus gene

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.

Contig / repliconNZ_AEZX02000014.1All displayed genes belong to this local TCS context.

Neighborhood span264 747-268 959 nt4 213 nt

Members21 current focus gene

Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.

264 747 nt268 959 nt

+-EC50959_RS07765 EC50959_RS07760

Neighborhood gene cards

2 genes in the current local neighborhood.

EC50959_RS07765GCF_000194395#EC50959_RS07765

HKUnorthodoxCurrent focus

264 747-268 340 nt · Reverse (-)

Old locus EC50959_3828RefSeq WP_001399259.1

Open current gene

EC50959_RS07760GCF_000194395#EC50959_RS07760

RRunclassified

268 345-268 959 nt · Reverse (-)

Old locus EC50959_3829RefSeq WP_000991370.1

Open gene

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Available memberships1 cluster

HKOC_0161067HK

Run 6146 sequencesid 100%cov 80%

PFAM SBP_bac_3 + SBP_bac_3 + HisKA + HATPase_c + Response_reg + Hpt

Current gene is the representative sequence.

Selected clusterHKOC_0161067Run 6 · HK · 146 sequences

Representative sequenceGCF_000194395#EC50959_RS07765The current gene is the representative for this cluster.

PFAM architectureSBP_bac_3 + SBP_bac_3 + HisKA + HATPase_c + Response_reg + Hpt6 domains in the representative PFAM annotation.

Open in cluster search

PFAM architecture for HKOC_0161067

Simplified PFAM architecture for HKOC_0161067

PFAM domain coverage: 802 / 1197 aa (67.0%)

1 aa1197 aa

SBP_bac_3SBP_bac_3HisKAHATPase_cResponse_regHpt

Simplified architecture: SBP_bac_3 + SBP_bac_3 + HisKA + HATPase_c + Response_reg + Hpt
Raw architecture: SBP_bac_3[63-276] | SBP_bac_3[306-520] | HisKA[711-777] | HATPase_c[825-937] | Response_reg[961-1070] | Hpt[1104-1186]
Domain count: 6
Matched identifier: HKOC_0161067
Positioned domains: SBP_bac_3 63-276 ; SBP_bac_3 306-520 ; HisKA 711-777 ; HATPase_c 825-937 ; Response_reg 961-1070 ; Hpt 1104-1186

Cluster members and taxonomy

Representative gene: GCF_000194395#EC50959_RS07765

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 869 684 · GCF_000194395

AssemblyASM19439v2 · Contighaploid

Genome composition5 416 945 bp · 50,5% GCEscherichia coli 5.0959

Signal transduction countsGenes 62 · HK 30 · RR 32CheA 1 · PP 0

Ranked taxonomy7 ranked levels available

SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia

Lineage path7 lineage nodes

1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Open genome Search genes in genome Search HK genes NCBI assembly files

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