Gene detail

DORFOR_RS00745

Histidine kinase, Hybrid

Dorea formicigenerans ATCC 27755 · GCF_000169235

ClassHKTypeHybridLength640 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_000169235#DORFOR_RS00745Stable P2CS identifier used across views.
GenomeGCF_000169235Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Dorea
Selected clusterHKOC_0921069Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_005330422.1 · B0G1U4 · MIST4 DORFOR_RS00745RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length640 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage293 / 640 aa (45.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa640 aa
HisKA: 265-331 aa (67 aa)1HATPase_c: 384-495 aa (112 aa)2Response_reg: 520-633 aa (114 aa)3
Domain-by-domain annotation3 items
1 HisKA#1
265-331 aa · 67 aa · 10.5% of protein
Raw tokenHisKA:265:5.82e-18:331:67:64
2 HATPase_c#2
384-495 aa · 112 aa · 17.5% of protein
Raw tokenHATPase_c:384:2.21e-29:495:112:109
3 Response_reg#3
520-633 aa · 114 aa · 17.8% of protein
Raw tokenResponse_reg:520:7.74e-29:633:114:111
  • Raw architecture: HisKA:265:5.82e-18:331:67:64#HATPase_c:384:2.21e-29:495:112:109#Response_reg:520:7.74e-29:633:114:111
  • Domain description: 1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labeltriadGCF_000169235::NZ_AAXA02000005.1::G00043
Group size33 locus tags listed below.
HK / RR2 / 1Counts resolved for the local TCS neighborhood.
Context span3535-9211Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDORFOR_00165RefSeq proteinWP_005330422.1
Context group IDGCF_000169235::NZ_AAXA02000005.1::G00043
Context members
DORFOR_RS16360DORFOR_RS00740DORFOR_RS00745
Partner locus tags
DORFOR_RS16360DORFOR_RS00740DORFOR_RS00745
Partner old locus tags
DORFOR_00163DORFOR_00164DORFOR_00165

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_005330422.1Primary protein accession used for annex mappings.
UniProt accessionB0G1U4Primary UniProt accession resolved in the annex database.
UniProt IDB0G1U4_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDORFOR_RS00745Primary locus identifier stored in the genes table.
Old locus tagDORFOR_00165Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AAXA02000005.1Sequence record reported by the local genomic context database.
Genomic interval7 289-9 211 nt1 923 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span3 535-9 211 ntGCF_000169235::NZ_AAXA02000005.1::G00043

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000169235::NZ_AAXA02000005.1::G00043

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AAXA02000005.1All displayed genes belong to this local TCS context.
Neighborhood span3 535-9 211 nt5 677 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 535 nt9 211 nt
Neighborhood gene cards

3 genes in the current local neighborhood.

DORFOR_RS16360GCF_000169235#DORFOR_RS16360
RRunclassified

3 535-4 098 nt · Forward (+)

Old locus DORFOR_00163RefSeq WP_081445642.1
DORFOR_RS00740GCF_000169235#DORFOR_RS00740
HKHybrid

4 387-7 260 nt · Forward (+)

Old locus DORFOR_00164RefSeq WP_005330419.1
DORFOR_RS00745GCF_000169235#DORFOR_RS00745
HKHybridCurrent focus

7 289-9 211 nt · Forward (+)

Old locus DORFOR_00165RefSeq WP_005330422.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0921069Run 6 · HK · 2 sequences
Representative sequenceGCF_000169235#DORFOR_RS00745The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0921069

Simplified PFAM architecture for HKOC_0921069

PFAM domain coverage: 295 / 640 aa (46.1%)

1 aa640 aa
HisKA: 265-330 aaHisKAHATPase_c: 381-494 aaHATPase_cResponse_reg: 520-634 aaResponse_reg
HisKAHATPase_cResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg
  • Raw architecture: HisKA[265-330] | HATPase_c[381-494] | Response_reg[520-634]
  • Domain count: 3
  • Matched identifier: HKOC_0921069
  • Positioned domains: HisKA 265-330 ; HATPase_c 381-494 ; Response_reg 520-634
Cluster members and taxonomy
Visualization

Representative gene: GCF_000169235#DORFOR_RS00745

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 411 461 · GCF_000169235
AssemblyASM16923v1 · Contighaploid
Genome composition3 186 031 bp · 41,0% GCDorea formicigenerans ATCC 27755
Signal transduction countsGenes 84 · HK 44 · RR 39CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusDorea
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Dorea

Related genes

Preview from the same derived genome key