Gene detail

CLOSTHATH_RS01225

Histidine kinase, Hybrid

Hungatella hathewayi DSM 13479 · GCF_000160095

ClassHKTypeHybridLength875 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_000160095#CLOSTHATH_RS01225Stable P2CS identifier used across views.
GenomeGCF_000160095Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella
Selected clusterHKOC_0453054Run 6 · 6 sequences · id 100% · cov 80% · representative
External referencesWP_006770847.1 · D3A9L9 · MIST4 CLOSTHATH_RS01225RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length875 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage414 / 875 aa (47.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa875 aa
HisKA: 359-424 aa (66 aa)1HATPase_c: 473-588 aa (116 aa)2Response_reg: 609-724 aa (116 aa)3Response_reg: 752-867 aa (116 aa)4
Domain-by-domain annotation4 items
1 HisKA#1
359-424 aa · 66 aa · 7.5% of protein
Raw tokenHisKA:359:0.00000000000000692:424:66:64
2 HATPase_c#2
473-588 aa · 116 aa · 13.3% of protein
Raw tokenHATPase_c:473:1.99e-29:588:116:109
3 Response_reg#3
609-724 aa · 116 aa · 13.3% of protein
Raw tokenResponse_reg:609:4.64e-25:724:116:111
4 Response_reg#4
752-867 aa · 116 aa · 13.3% of protein
Raw tokenResponse_reg:752:1.75e-23:867:116:111
  • Raw architecture: HisKA:359:0.00000000000000692:424:66:64#HATPase_c:473:1.99e-29:588:116:109#Response_reg:609:4.64e-25:724:116:111#Response_reg:752:1.75e-23:867:116:111
  • Domain description: 1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labeltriadGCF_000160095::NZ_GG667608.1::G00135
Group size33 locus tags listed below.
HK / RR2 / 1Counts resolved for the local TCS neighborhood.
Context span110797-115732Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCLOSTHATH_00290RefSeq proteinWP_006770847.1
Context group IDGCF_000160095::NZ_GG667608.1::G00135
Context members
CLOSTHATH_RS01225CLOSTHATH_RS01235CLOSTHATH_RS01240
Partner locus tags
CLOSTHATH_RS01225CLOSTHATH_RS01235CLOSTHATH_RS01240
Partner old locus tags
CLOSTHATH_00290CLOSTHATH_00292CLOSTHATH_00293

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_006770847.1Primary protein accession used for annex mappings.
UniProt accessionD3A9L9Primary UniProt accession resolved in the annex database.
UniProt IDD3A9L9_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCLOSTHATH_RS01225Primary locus identifier stored in the genes table.
Old locus tagCLOSTHATH_00290Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GG667608.1Sequence record reported by the local genomic context database.
Genomic interval110 797-113 424 nt2 628 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span110 797-115 732 ntGCF_000160095::NZ_GG667608.1::G00135

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000160095::NZ_GG667608.1::G00135

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GG667608.1All displayed genes belong to this local TCS context.
Neighborhood span110 797-115 732 nt4 936 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
110 797 nt115 732 nt
Neighborhood gene cards

3 genes in the current local neighborhood.

CLOSTHATH_RS01235GCF_000160095#CLOSTHATH_RS01235
RROmpR

113 898-114 581 nt · Forward (+)

Old locus CLOSTHATH_00292RefSeq WP_006770849.1
CLOSTHATH_RS01240GCF_000160095#CLOSTHATH_RS01240
HKClassic

114 575-115 732 nt · Forward (+)

Old locus CLOSTHATH_00293RefSeq WP_006770850.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0453054Run 6 · HK · 6 sequences
Representative sequenceGCF_000160095#CLOSTHATH_RS01225The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0453054

Simplified PFAM architecture for HKOC_0453054

PFAM domain coverage: 413 / 875 aa (47.2%)

1 aa875 aa
HisKA: 359-424 aaHisKAHATPase_c: 473-588 aaHATPase_cResponse_reg: 609-723 aaResponse_regResponse_reg: 752-867 aaResponse_reg
HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: HisKA[359-424] | HATPase_c[473-588] | Response_reg[609-723] | Response_reg[752-867]
  • Domain count: 4
  • Matched identifier: HKOC_0453054
  • Positioned domains: HisKA 359-424 ; HATPase_c 473-588 ; Response_reg 609-723 ; Response_reg 752-867
Cluster members and taxonomy
Visualization

Representative gene: GCF_000160095#CLOSTHATH_RS01225

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 566 550 · GCF_000160095
AssemblyASM16009v1 · Scaffoldhaploid
Genome composition7 163 884 bp · 48,0% GCHungatella hathewayi DSM 13479
Signal transduction countsGenes 227 · HK 106 · RR 114CheA 0 · PP 7
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusHungatella
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Hungatella

Related genes

Preview from the same derived genome key