Gene detail

ANASTE_RS02020

Histidine kinase, Hybrid

Anaerofustis stercorihominis DSM 17244 · GCF_000154825

ClassHKTypeHybridLength1210 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000154825#ANASTE_RS02020Stable P2CS identifier used across views.
GenomeGCF_000154825Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Anaerofustis
Selected clusterHKOC_0152648Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_007049229.1 · B1C7S8 · MIST4 ANASTE_RS02020RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_3HisKAHATPase_cResponse_reg
Protein length1210 aaLength used to scale native and Biotite-like views.
Annotated domains77 with usable coordinates.
Domain coverage626 / 1210 aa (51.7%)Merged over positioned domains only.
Domain description3 PAS_3,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1210 aa
PAS_3: 174-249 aa (76 aa)1PAS_3: 317-399 aa (83 aa)2PAS_3: 449-533 aa (85 aa)3HisKA: 700-766 aa (67 aa)4HATPase_c: 813-924 aa (112 aa)5Response_reg: 947-1031 aa (85 aa)6Response_reg: 1088-1205 aa (118 aa)7
Domain-by-domain annotation7 items
1 PAS_3#1
174-249 aa · 76 aa · 6.3% of protein
Raw tokenPAS_3:174:0.00000000305:249:77:89
2 PAS_3#2
317-399 aa · 83 aa · 6.9% of protein
Raw tokenPAS_3:317:0.0000000000000441:399:83:89
3 PAS_3#3
449-533 aa · 85 aa · 7.0% of protein
Raw tokenPAS_3:449:3.2e-17:533:85:89
4 HisKA#4
700-766 aa · 67 aa · 5.5% of protein
Raw tokenHisKA:700:8.5e-18:766:67:64
5 HATPase_c#5
813-924 aa · 112 aa · 9.3% of protein
Raw tokenHATPase_c:813:2.88e-28:924:112:109
6 Response_reg#6
947-1031 aa · 85 aa · 7.0% of protein
Raw tokenResponse_reg:947:0.000000000000694:1031:85:111
7 Response_reg#7
1088-1205 aa · 118 aa · 9.8% of protein
Raw tokenResponse_reg:1088:3.8e-26:1205:118:111
  • Raw architecture: PAS_3:174:0.00000000305:249:77:89#PAS_3:317:0.0000000000000441:399:83:89#PAS_3:449:3.2e-17:533:85:89#HisKA:700:8.5e-18:766:67:64#HATPase_c:813:2.88e-28:924:112:109#Response_reg:947:0.000000000000694:1031:85:111#Response_reg:1088:3.8e-26:1205:118:111
  • Domain description: 3 PAS_3,1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000154825::NZ_DS560015.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span414732-419477Genomic interval covered by the local TCS group.
Identifiers
Old locus tagANASTE_00782RefSeq proteinWP_007049229.1
Context group IDGCF_000154825::NZ_DS560015.1::G00018
Context members
ANASTE_RS02015ANASTE_RS02020
Partner locus tags
ANASTE_RS02015ANASTE_RS02020
Partner old locus tags
ANASTE_00781ANASTE_00782
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_007049229.1Primary protein accession used for annex mappings.
UniProt accessionB1C7S8Primary UniProt accession resolved in the annex database.
UniProt IDB1C7S8_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagANASTE_RS02020Primary locus identifier stored in the genes table.
Old locus tagANASTE_00782Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_DS560015.1Sequence record reported by the local genomic context database.
Genomic interval415 845-419 477 nt3 633 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span414 732-419 477 ntGCF_000154825::NZ_DS560015.1::G00018

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000154825::NZ_DS560015.1::G00018

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_DS560015.1All displayed genes belong to this local TCS context.
Neighborhood span414 732-419 477 nt4 746 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
414 732 nt419 477 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ANASTE_RS02015GCF_000154825#ANASTE_RS02015
RRRpfG

414 732-415 820 nt · Forward (+)

Old locus ANASTE_00781RefSeq WP_007049228.1
ANASTE_RS02020GCF_000154825#ANASTE_RS02020
HKHybridCurrent focus

415 845-419 477 nt · Forward (+)

Old locus ANASTE_00782RefSeq WP_007049229.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0152648Run 6 · HK · 2 sequences
Representative sequenceGCF_000154825#ANASTE_RS02020The current gene is the representative for this cluster.
PFAM architecturePAS_3 + PAS_3 + PAS_3 + HisKA + HATPase_c + Response_reg + Response_reg7 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0152648

Simplified PFAM architecture for HKOC_0152648

PFAM domain coverage: 652 / 1210 aa (53.9%)

1 aa1210 aa
PAS_3: 175-249 aaPAS_3PAS_3: 318-399 aaPAS_3PAS_3: 450-532 aaPAS_3HisKA: 700-766 aaHisKAHATPase_c: 813-925 aaHATPase_cResponse_reg: 947-1061 aaResponse_regResponse_reg: 1088-1204 aaResponse_reg
PAS_3PAS_3PAS_3HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: PAS_3 + PAS_3 + PAS_3 + HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: PAS_3[175-249] | PAS_3[318-399] | PAS_3[450-532] | HisKA[700-766] | HATPase_c[813-925] | Response_reg[947-1061] | Response_reg[1088-1204]
  • Domain count: 7
  • Matched identifier: HKOC_0152648
  • Positioned domains: PAS_3 175-249 ; PAS_3 318-399 ; PAS_3 450-532 ; HisKA 700-766 ; HATPase_c 813-925 ; Response_reg 947-1061 ; Response_reg 1088-1204
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154825#ANASTE_RS02020

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 445 971 · GCF_000154825
AssemblyASM15482v1 · Scaffoldreference genome · haploid
Genome composition2 284 703 bp · 33,5% GCAnaerofustis stercorihominis DSM 17244
Signal transduction countsGenes 38 · HK 22 · RR 14CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusAnaerofustis
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Anaerofustis

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Preview from the same derived genome key