Gene detail

HMPREF9319_RS08545

Histidine kinase, Classic

Streptococcus equinus ATCC 700338 · GCF_000146405

ClassHKTypeClassicLength550 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000146405#HMPREF9319_RS08545Stable P2CS identifier used across views.
GenomeGCF_000146405Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Selected clusterHKOC_1292503Run 6 · 12 sequences · id 100% · cov 80% · representative
External referencesWP_003066477.1 · E0PG10 · MIST4 HMPREF9319_RS08545RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

sCache_likePAS_9HisKAHATPase_c
Protein length550 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage356 / 550 aa (64.7%)Merged over positioned domains only.
Domain description1 sCache_like,1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa550 aa
sCache_like: 36-125 aa (90 aa)1PAS_9: 233-324 aa (92 aa)2HisKA: 332-396 aa (65 aa)3HATPase_c: 440-548 aa (109 aa)4
Domain-by-domain annotation4 items
1 sCache_like#1
36-125 aa · 90 aa · 16.4% of protein
Raw tokensCache_like:36:0.000000109:125:99:114
2 PAS_9#2
233-324 aa · 92 aa · 16.7% of protein
Raw tokenPAS_9:233:0.00000021:324:101:102
3 HisKA#3
332-396 aa · 65 aa · 11.8% of protein
Raw tokenHisKA:332:0.00000000000000579:396:65:64
4 HATPase_c#4
440-548 aa · 109 aa · 19.8% of protein
Raw tokenHATPase_c:440:3.49e-29:548:109:109
  • Raw architecture: sCache_like:36:0.000000109:125:99:114#PAS_9:233:0.00000021:324:101:102#HisKA:332:0.00000000000000579:396:65:64#HATPase_c:440:3.49e-29:548:109:109
  • Domain description: 1 sCache_like,1 PAS_9,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000146405::NZ_GL397128.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1787432-1789754Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9319_1783RefSeq proteinWP_003066477.1
Context group IDGCF_000146405::NZ_GL397128.1::G00014
Context members
HMPREF9319_RS08545HMPREF9319_RS08550
Partner locus tags
HMPREF9319_RS08545HMPREF9319_RS08550
Partner old locus tags
HMPREF9319_1783HMPREF9319_1784
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003066477.1Primary protein accession used for annex mappings.
UniProt accessionE0PG10Primary UniProt accession resolved in the annex database.
UniProt IDE0PG10_STREIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9319_RS08545Primary locus identifier stored in the genes table.
Old locus tagHMPREF9319_1783Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL397128.1Sequence record reported by the local genomic context database.
Genomic interval1 787 432-1 789 084 nt1 653 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 787 432-1 789 754 ntGCF_000146405::NZ_GL397128.1::G00014

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000146405::NZ_GL397128.1::G00014

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL397128.1All displayed genes belong to this local TCS context.
Neighborhood span1 787 432-1 789 754 nt2 323 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 787 432 nt1 789 754 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9319_RS08545GCF_000146405#HMPREF9319_RS08545
HKClassicCurrent focus

1 787 432-1 789 084 nt · Reverse (-)

Old locus HMPREF9319_1783RefSeq WP_003066477.1
HMPREF9319_RS08550GCF_000146405#HMPREF9319_RS08550
RROmpR

1 789 077-1 789 754 nt · Reverse (-)

Old locus HMPREF9319_1784RefSeq WP_003066479.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1292503Run 6 · HK · 12 sequences
Representative sequenceGCF_000146405#HMPREF9319_RS08545The current gene is the representative for this cluster.
PFAM architecturePAS_8 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1292503

Simplified PFAM architecture for HKOC_1292503

PFAM domain coverage: 224 / 550 aa (40.7%)

1 aa550 aa
PAS_8: 225-277 aaPAS_8HisKA: 332-396 aaHisKAHATPase_c: 443-548 aaHATPase_c
PAS_8HisKAHATPase_c
  • Simplified architecture: PAS_8 + HisKA + HATPase_c
  • Raw architecture: PAS_8[225-277] | HisKA[332-396] | HATPase_c[443-548]
  • Domain count: 3
  • Matched identifier: HKOC_1292503
  • Positioned domains: PAS_8 225-277 ; HisKA 332-396 ; HATPase_c 443-548
Cluster members and taxonomy
Visualization

Representative gene: GCF_000146405#HMPREF9319_RS08545

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 864 569 · GCF_000146405
AssemblyASM14640v1 · Scaffoldhaploid
Genome composition2 083 084 bp · 37,0% GCStreptococcus equinus ATCC 700338
Signal transduction countsGenes 30 · HK 14 · RR 15CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyStreptococcaceaeGenusStreptococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Streptococcaceae7Streptococcus

Related genes

Preview from the same derived genome key