Gene detail

HMPREF9319_RS06880

Histidine kinase, Classic

Streptococcus equinus ATCC 700338 · GCF_000146405

ClassHKTypeClassicLength450 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000146405#HMPREF9319_RS06880Stable P2CS identifier used across views.
GenomeGCF_000146405Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Selected clusterHKOC_1962134Run 6 · 26 sequences · id 100% · cov 80% · representative
External referencesWP_003065768.1 · E0PF12 · MIST4 HMPREF9319_RS06880RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_9HisKAHATPase_c
Protein length450 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage277 / 450 aa (61.6%)Merged over positioned domains only.
Domain description1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa450 aa
PAS_9: 104-201 aa (98 aa)1HisKA: 208-274 aa (67 aa)2HATPase_c: 326-437 aa (112 aa)3
Domain-by-domain annotation3 items
1 PAS_9#1
104-201 aa · 98 aa · 21.8% of protein
Raw tokenPAS_9:104:0.000000221:201:104:102
2 HisKA#2
208-274 aa · 67 aa · 14.9% of protein
Raw tokenHisKA:208:1.5e-16:274:67:64
3 HATPase_c#3
326-437 aa · 112 aa · 24.9% of protein
Raw tokenHATPase_c:326:1.26e-34:437:112:109
  • Raw architecture: PAS_9:104:0.000000221:201:104:102#HisKA:208:1.5e-16:274:67:64#HATPase_c:326:1.26e-34:437:112:109
  • Domain description: 1 PAS_9,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000146405::NZ_GL397128.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1446700-1448755Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9319_1435RefSeq proteinWP_003065768.1
Context group IDGCF_000146405::NZ_GL397128.1::G00011
Context members
HMPREF9319_RS06880HMPREF9319_RS06885
Partner locus tags
HMPREF9319_RS06880HMPREF9319_RS06885
Partner old locus tags
HMPREF9319_1435HMPREF9319_1436
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003065768.1Primary protein accession used for annex mappings.
UniProt accessionE0PF12Primary UniProt accession resolved in the annex database.
UniProt IDE0PF12_STREIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9319_RS06880Primary locus identifier stored in the genes table.
Old locus tagHMPREF9319_1435Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL397128.1Sequence record reported by the local genomic context database.
Genomic interval1 446 700-1 448 052 nt1 353 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 446 700-1 448 755 ntGCF_000146405::NZ_GL397128.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000146405::NZ_GL397128.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL397128.1All displayed genes belong to this local TCS context.
Neighborhood span1 446 700-1 448 755 nt2 056 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 446 700 nt1 448 755 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9319_RS06880GCF_000146405#HMPREF9319_RS06880
HKClassicCurrent focus

1 446 700-1 448 052 nt · Reverse (-)

Old locus HMPREF9319_1435RefSeq WP_003065768.1
HMPREF9319_RS06885GCF_000146405#HMPREF9319_RS06885
RROmpR

1 448 045-1 448 755 nt · Reverse (-)

Old locus HMPREF9319_1436RefSeq WP_003065770.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1962134Run 6 · HK · 26 sequences
Representative sequenceGCF_000146405#HMPREF9319_RS06880The current gene is the representative for this cluster.
PFAM architectureCovS-like_HAMP + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1962134

Simplified PFAM architecture for HKOC_1962134

PFAM domain coverage: 326 / 450 aa (72.4%)

1 aa450 aa
CovS-like_HAMP: 32-86 aaCovS-like_HAMPPAS: 95-189 aaPASHisKA: 209-273 aaHisKAHATPase_c: 326-436 aaHATPase_c
CovS-like_HAMPPASHisKAHATPase_c
  • Simplified architecture: CovS-like_HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: CovS-like_HAMP[32-86] | PAS[95-189] | HisKA[209-273] | HATPase_c[326-436]
  • Domain count: 4
  • Matched identifier: HKOC_1962134
  • Positioned domains: CovS-like_HAMP 32-86 ; PAS 95-189 ; HisKA 209-273 ; HATPase_c 326-436
Cluster members and taxonomy
Visualization

Representative gene: GCF_000146405#HMPREF9319_RS06880

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 864 569 · GCF_000146405
AssemblyASM14640v1 · Scaffoldhaploid
Genome composition2 083 084 bp · 37,0% GCStreptococcus equinus ATCC 700338
Signal transduction countsGenes 30 · HK 14 · RR 15CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyStreptococcaceaeGenusStreptococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Streptococcaceae7Streptococcus

Related genes

Preview from the same derived genome key