Gene detail

B2C47_RS00455

Histidine kinase, Classic

Clostridioides difficile · GCF_900165335

ClassHKTypeClassicLength530 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_900165335#B2C47_RS00455Stable P2CS identifier used across views.
GenomeGCF_900165335Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1359392Run 6 · 4 sequences · id 100% · cov 80% · representative
External referencesWP_170878251.1 · MIST4 B2C47_RS00455RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length530 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 530 aa (28.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for B2C47_RS00455
Domain-by-domain annotation2 items
1 HisKA#1
309-375 aa · 67 aa · 12.6% of protein
Raw tokenHisKA:309:0.0000000000000124:375:67:64
2 HATPase_c#2
428-513 aa · 86 aa · 16.2% of protein
Raw tokenHATPase_c:428:0.000000079:513:90:109
  • Raw architecture: HisKA:309:0.0000000000000124:375:67:64#HATPase_c:428:0.000000079:513:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_900165335::NZ_FUQB01000001.1::G00041
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span106875-109152Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSAMEA3375148_00092RefSeq proteinWP_170878251.1
Context group IDGCF_900165335::NZ_FUQB01000001.1::G00041
Context members
B2C47_RS00455B2C47_RS00460
Partner locus tags
B2C47_RS00455B2C47_RS00460
Partner old locus tags
SAMEA3375148_00092SAMEA3375148_00093
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_170878251.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB2C47_RS00455Primary locus identifier stored in the genes table.
Old locus tagSAMEA3375148_00092Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_FUQB01000001.1Sequence record reported by the local genomic context database.
Genomic interval106 875-108 467 nt1 593 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span106 875-109 152 ntGCF_900165335::NZ_FUQB01000001.1::G00041

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_900165335::NZ_FUQB01000001.1::G00041

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_FUQB01000001.1All displayed genes belong to this local TCS context.
Neighborhood span106 875-109 152 nt2 278 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
106 875 nt109 152 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B2C47_RS00455GCF_900165335#B2C47_RS00455
HKClassicCurrent focus

106 875-108 467 nt · Reverse (-)

Old locus SAMEA3375148_00092RefSeq WP_170878251.1
B2C47_RS00460GCF_900165335#B2C47_RS00460
RROmpR

108 436-109 152 nt · Reverse (-)

Old locus SAMEA3375148_00093RefSeq WP_077716800.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1359392Run 6 · HK · 4 sequences
Representative sequenceGCF_900165335#B2C47_RS00455The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1359392

Simplified PFAM architecture for HKOC_1359392

PFAM domain coverage: 188 / 530 aa (35.5%)

1 aa530 aa
HAMP: 255-295 aaHAMPHisKA: 310-375 aaHisKAHATPase_c: 427-507 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[255-295] | HisKA[310-375] | HATPase_c[427-507]
  • Domain count: 3
  • Matched identifier: HKOC_1359392
  • Positioned domains: HAMP 255-295 ; HisKA 310-375 ; HATPase_c 427-507
Cluster members and taxonomy
Visualization

Representative gene: GCF_900165335#B2C47_RS00455

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_900165335
Assembly16780_8#82 · Scaffoldhaploid
Genome composition4 281 476 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 50 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key